DRSC/TRiP Functional Genomics Resources

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Protein Alignment ranshi and topi

DIOPT Version :9

Sequence 1:NP_649824.1 Gene:ranshi / 41041 FlyBaseID:FBgn0037620 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_649945.1 Gene:topi / 41199 FlyBaseID:FBgn0037751 Length:814 Species:Drosophila melanogaster


Alignment Length:360 Identity:91/360 - (25%)
Similarity:142/360 - (39%) Gaps:91/360 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 FEKRNQTTLEHIK-----LLTGAVLKNCSTLPNRLCASC--------QTCLQQAISFRERCLE-- 71
            |...||.|....|     |:.|:||:         |..|        :..:..|....||..|  
  Fly   336 FATSNQNTNPPKKEMFSSLILGSVLQ---------CEFCEYIFADIAELLVHSASHVAERRFECT 391

  Fly    72 --------VQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSG 128
                    .:...:|.|.|..|:|   |:.:|             :::.:.|....|...::   
  Fly   392 ACDIQMNTAKEASIHFQTDCIFMR---EAIRS-------------LNVTLSRYFVCNVCELK--- 437

  Fly   129 FKVEDILNE---------SKINEDE-----PNNEDDIDYS-EMDYLIYESDTEVDAKQELKSDSE 178
            |...|:|.|         .::||:.     |.:..|:::. ..|:|.:..:..::.|        
  Fly   438 FANTDLLQEHRCTSFHYFPRLNENGKKLLLPCDFCDVNFEFAHDFLAHSEEKHLNKK-------- 494

  Fly   179 NPKKRRNRRNPRDSN-RTFFCEECGNHIKDRISFILHCKRHRGVKEFGC--EFCEDRFCTPAELK 240
              |:.:..||..... |.:.|:.||...........|.:.|:|||.|.|  |.|:.:|....:|.
  Fly   495 --KREKETRNTGAGRIRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLN 557

  Fly   241 RHIRK-HTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTG 304
            .|||| ||||:|:.|..|.:.|...|...:|...|..||.:.|:||...|..:..||||..:|||
  Fly   558 DHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTG 622

  Fly   305 EKAFRCDLCDKLF-----------SRYTHLTTHYR 328
            ||.:.|..|.|.|           :|::||..:.|
  Fly   623 EKPYSCLFCTKTFRQRGDRDKHIRARHSHLDANSR 657

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ranshiNP_649824.1 zf-AD 5..77 CDD:214871 15/77 (19%)
C2H2 Zn finger 198..218 CDD:275368 4/19 (21%)
COG5048 222..>276 CDD:227381 22/56 (39%)
C2H2 Zn finger 226..246 CDD:275368 9/22 (41%)
zf-H2C2_2 238..262 CDD:290200 12/24 (50%)
C2H2 Zn finger 254..274 CDD:275368 5/19 (26%)
zf-H2C2_2 269..291 CDD:290200 8/21 (38%)
C2H2 Zn finger 282..302 CDD:275368 8/19 (42%)
zf-H2C2_2 295..319 CDD:290200 13/34 (38%)
C2H2 Zn finger 310..328 CDD:275368 7/28 (25%)
topiNP_649945.1 C2H2 Zn finger 230..250 CDD:275368
C2H2 Zn finger 277..297 CDD:275368
C2H2 Zn finger 431..453 CDD:275368 5/24 (21%)
COG5048 <450..647 CDD:227381 59/206 (29%)
C2H2 Zn finger 469..490 CDD:275368 3/20 (15%)
zf-C2H2 511..533 CDD:278523 4/21 (19%)
C2H2 Zn finger 513..564 CDD:275368 18/50 (36%)
C2H2 Zn finger 541..561 CDD:275368 6/19 (32%)
zf-H2C2_2 555..581 CDD:290200 13/25 (52%)
C2H2 Zn finger 572..592 CDD:275368 5/19 (26%)
zf-H2C2_2 585..609 CDD:290200 8/23 (35%)
zf-C2H2 598..620 CDD:278523 8/21 (38%)
C2H2 Zn finger 600..620 CDD:275368 8/19 (42%)
zf-H2C2_2 612..637 CDD:290200 13/24 (54%)
C2H2 Zn finger 628..646 CDD:275368 4/17 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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