DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG8159

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	142/366 - (38%)
Similarity:	204/366 - (55%)	Gaps:	66/366 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERC 69
            |||.|...|:..:||.:|.......|:.|.||||.:|:....||:.:|.:|||.|:.|||||:||
  Fly     5 VCRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFRDRC 69

  Fly    70 LEVQR---ELLHSQDDEDFLRICQESPKSVLEQEELELDLA--------EISIEVERLDDLNEGP 123
            |..|:   |.|...:::.|....:.|.:|..::.|   |.|        |:.|::|.|.
  Fly    70 LRSQKIFEESLVRNEEDTFRSSVRRSARSQRQRHE---DTAPKTPASPLEVMIKLESLS------ 125

  Fly   124 IQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPK------- 181
                             |.||   |||    .:|:|  :|..|.|.:..:|:.|.:.:
  Fly   126 -----------------NGDE---EDD----GIDHL--DSCNEADMELAIKAMSSSTEDDGTTSP 164

  Fly   182 ---KRRNRR----NPRDSNRT------FFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRF 233
               ||..||    ..:..|||      |||::|||:|..:.||..|.::|.|::.|.||.|..||
  Fly   165 VRLKRTRRRGLKKGGKGENRTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARF 229

  Fly   234 CTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNH 298
            .:..|||.|...|||::.|:||:|.|::.:||.||:|||||||:|||:|.:|..:||.|||||||
  Fly   230 LSSGELKGHQVMHTGDRKFQCRYCDRTYVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNH 294

  Fly   299 MLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKA 339
            ||:||||:.|||:||.:.|:|.|||.||:|||.|:.|::|:
  Fly   295 MLIHTGERLFRCELCHRSFARPTHLKTHFRSNTHKHNLEKS 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	32/74 (43%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		COG5048	222..>276	CDD:227381	27/53 (51%)
		C2H2 Zn finger	226..246	CDD:275368	9/19 (47%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	11/19 (58%)
		zf-H2C2_2	269..291	CDD:290200	13/21 (62%)
		C2H2 Zn finger	282..302	CDD:275368	13/19 (68%)
		zf-H2C2_2	295..319	CDD:290200	16/23 (70%)
		C2H2 Zn finger	310..328	CDD:275368	10/17 (59%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	31/72 (43%)
		C2H2 Zn finger	194..214	CDD:275368	8/19 (42%)
		COG5048	<197..322	CDD:227381	68/124 (55%)
		zf-H2C2_2	206..231	CDD:290200	11/24 (46%)
		C2H2 Zn finger	222..242	CDD:275368	9/19 (47%)
		C2H2 Zn finger	250..270	CDD:275368	11/19 (58%)
		zf-H2C2_2	265..287	CDD:290200	13/21 (62%)
		C2H2 Zn finger	278..298	CDD:275368	13/19 (68%)
		zf-H2C2_2	291..315	CDD:290200	16/23 (70%)
		C2H2 Zn finger	306..328	CDD:275368	13/21 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447754
Domainoid	1	1.000	77	1.000	Domainoid score	I15703
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890