DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and ouib

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	122/338 - (36%)
Similarity:	188/338 - (55%)	Gaps:	37/338 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERC 69
            |||.||::...|:|||:|:..|:..|:|:.:::|..|.:...:|..:|..||..|:.|::||:.|
  Fly     5 VCRVCGRQKICEKSLNLFDLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALAFRKLC 69

  Fly    70 LEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDI 134
            ::.|.:.|..:||.      ....:...:..|||.:....|    ......||.:....|:|
  Fly    70 IKTQTKWLTIEDDS------SSGDEDTNDNSELESEKCAFS----DFGKKKEGELVEETFQV--- 121

  Fly   135 LNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSEN----PKKRRNRRNPRDSNRT 195
                 :.|:||          ||..:..     |||.:|:.|..:    |.::..:.:.:..::.
  Fly   122 -----LIEEEP----------MDKTLNR-----DAKAQLREDGIDEKCVPSQKIIKVSTKLDDQI 166

  Fly   196 FFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRS 260
            :.||.||.|...:.:|..|.::|||.:.|||:.|:.||.:..||:.|.|.||||:||.||.|.:.
  Fly   167 YICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAGELRAHHRVHTGEQPFACRFCEKR 231

  Fly   261 FSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTT 325
            :..|..||.|||||||:||:||:||...|||:|:|||||::||||:.||||:||:.|.|..||.|
  Fly   232 YVSYMGRLIHERTHTNDRPYVCEECGKKFTTAYVLKNHMVIHTGERNFRCDICDRSFQRKAHLVT 296

  Fly   326 HYRSNAHRRNMQK 338
            |.||..|.:|::|
  Fly   297 HTRSMMHLQNVKK 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	25/71 (35%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		COG5048	222..>276	CDD:227381	27/53 (51%)
		C2H2 Zn finger	226..246	CDD:275368	8/19 (42%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..291	CDD:290200	14/21 (67%)
		C2H2 Zn finger	282..302	CDD:275368	12/19 (63%)
		zf-H2C2_2	295..319	CDD:290200	16/23 (70%)
		C2H2 Zn finger	310..328	CDD:275368	10/17 (59%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	25/72 (35%)
		COG5048	<158..300	CDD:227381	70/141 (50%)
		C2H2 Zn finger	169..189	CDD:275368	7/19 (37%)
		C2H2 Zn finger	197..217	CDD:275368	8/19 (42%)
		zf-H2C2_2	209..234	CDD:290200	13/24 (54%)
		C2H2 Zn finger	225..245	CDD:275368	9/19 (47%)
		zf-H2C2_2	241..262	CDD:290200	14/20 (70%)
		C2H2 Zn finger	253..273	CDD:275368	12/19 (63%)
		zf-H2C2_2	266..288	CDD:290200	15/21 (71%)
		C2H2 Zn finger	281..299	CDD:275368	10/17 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447752
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890