DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ranshi and nom

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	114/347 - (32%)
Similarity:	175/347 - (50%)	Gaps:	41/347 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERC 69
            |||.||:.....:::.:|:...|..|..|:|:||.:|:.....|:.:|..|||.||.|:.||.:|
  Fly     5 VCRVCGRSRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMIFRRQC 69

  Fly    70 LEVQRELLHSQDDEDFLRICQESPKSVLEQEELE-LDLAEISIEVERLDDLNEGPIQSSGFKVED 133
            :..|::         ::.:.|.......|::::| .|.:......:|.......|::     :.|
  Fly    70 ILQQKK---------WVPLLQSDKVGASEEKKVEPNDPSTKKKTTKRRRGRPRMPLE-----IVD 120

  Fly   134 IL--NESKINEDEPNNEDDIDY-----SEMDYLIYESDT---EVDAKQE--LKSDSENPKKRRNR 186
            |:  ||||.:..|....|:.|.     :|.|  ..:||.   |:|...|  |:||.:.|..:.::
  Fly   121 IVVTNESKASAGESVGGDEFDQPVEISNEPD--ATDSDVNLEEIDLPDEDGLESDHDLPNVQIHK 183

  Fly   187 RNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRH-IRKHTGEK 250
                       |:.||....::.|.:.|...|.|::.:.|:.|...|...:|||.| :..||.|.
  Fly   184 -----------CDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFLVASELKAHNLTHHTLEP 237

  Fly   251 PFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDK 315
            ||.||:|.|.:.....|.||||.|||||||||.:|..|||.:.|||.||.||...:.:.||:||:
  Fly   238 PFACRYCDRRYFSVVGRKKHERVHTNERPFVCDQCGKAFTRTCILKAHMAVHQVVRKYSCDVCDR 302

  Fly   316 LFSRYTHLTTHYRSNAHRRNMQ 337
            .||...||.||:.||.|:||.:
  Fly   303 SFSLKKHLATHFISNTHKRNAE 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	25/71 (35%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	22/54 (41%)
		C2H2 Zn finger	226..246	CDD:275368	7/20 (35%)
		zf-H2C2_2	238..262	CDD:290200	13/24 (54%)
		C2H2 Zn finger	254..274	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..291	CDD:290200	16/21 (76%)
		C2H2 Zn finger	282..302	CDD:275368	10/19 (53%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	10/17 (59%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	25/79 (32%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		C2H2 Zn finger	212..261	CDD:275368	21/48 (44%)
		zf-H2C2_2	255..278	CDD:290200	16/22 (73%)
		C2H2 Zn finger	269..289	CDD:275368	10/19 (53%)
		zf-H2C2_2	282..305	CDD:290200	10/22 (45%)
		C2H2 Zn finger	297..313	CDD:275368	8/15 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447750
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890