DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ranshi and D19A

DIOPT Version :9

Sequence 1:NP_649824.1 Gene:ranshi / 41041 FlyBaseID:FBgn0037620 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_477304.1 Gene:D19A / 38718 FlyBaseID:FBgn0022935 Length:845 Species:Drosophila melanogaster


Alignment Length:577 Identity:108/577 - (18%)
Similarity:180/577 - (31%) Gaps:265/577 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 EGK------VCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNC----------STLPNR 50
            ||:      :||.|......:.:.:::            |:.|...|.|          ...|..
  Fly     3 EGRQYSIHSLCRICLNHLQNDAAYDLY------------LVPGLSKKLCFCTSLSVEQNDGFPKN 55

  Fly    51 LCASCQTCLQQAISFRERCLE-VQR--ELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIE 112
            ||..|.|.|.:...|:::|:: ||:  :|:.|.     :..||.|           .|:.:.::.
  Fly    56 LCTLCYTKLNELHDFQKQCVDSVQKFQDLVASN-----VFACQSS-----------FDVFDPNVA 104

  Fly   113 V-----ERLDDLNEGPI----------QSSGFKV--------EDILNESKINED----------- 143
            |     |..|.:|..|:          :...||:        |::..|:|:.||           
  Fly   105 VQDYPAEEEDHVNYDPLLNHKMELIENEEDVFKMLEHVDKEAEEVEKEAKVEEDDGGNVSVKMFD 169

  Fly   144 -----------------EPN-NEDDID------------------YSEMD--------------- 157
                             ||| ::|||.                  :|.:|               
  Fly   170 DDSSIESGNDNDHDLDFEPNSSDDDIPLAQRMRGPATGSGPQQDRFSNLDKPKPRPRGRPKKIKP 234

  Fly   158 -----YLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKR 217
                 ..:.:|.:|.|..::..|..:.||::|.....|..:|...|..|....|..|.:..|.|.
  Fly   235 PPPEEEELSDSSSESDDSEDGTSRGDKPKRKRIPIEERHLHRIIDCHICHQKFKKAIRYEEHMKY 299

  Fly   218 HRG-------------------------------------------------------------- 220
            |..                                                              
  Fly   300 HNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFHMKKVHG 364

  Fly   221 -------VKEFGCEFCEDRFCTPAELKRHIRKHTGEK-PFKCRHCSRSF------SDY------- 264
                   :::|.|..|:..|..|..||:|:.|||||: |:.|..|.:.|      .|:       
  Fly   365 ITKAAAPLRDFPCTECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGI 429

  Fly   265 ------------STRLK---HERTHTNERPFVCKECNNAFTTSYILKNHMLV------------- 301
                        :||.:   |..|||.|:.|.|::|::|......|.||:.|             
  Fly   430 KNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYC 494

  Fly   302 ----------------HTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKADTI 342
                            |||||...|.:|.|:|.....||.|.::: .:|::..|:.:
  Fly   495 GKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTH-EKRDLPPAEPL 550

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ranshiNP_649824.1 zf-AD 5..77 CDD:214871 17/84 (20%)
C2H2 Zn finger 198..218 CDD:275368 6/19 (32%)
COG5048 222..>276 CDD:227381 23/82 (28%)
C2H2 Zn finger 226..246 CDD:275368 7/19 (37%)
zf-H2C2_2 238..262 CDD:290200 12/30 (40%)
C2H2 Zn finger 254..274 CDD:275368 7/47 (15%)
zf-H2C2_2 269..291 CDD:290200 9/24 (38%)
C2H2 Zn finger 282..302 CDD:275368 7/48 (15%)
zf-H2C2_2 295..319 CDD:290200 13/52 (25%)
C2H2 Zn finger 310..328 CDD:275368 7/17 (41%)
D19ANP_477304.1 zf-AD 12..83 CDD:214871 17/82 (21%)
C2H2 Zn finger 343..362 CDD:275368 0/18 (0%)
C2H2 Zn finger 377..397 CDD:275368 7/19 (37%)
zf-H2C2_2 389..414 CDD:290200 11/24 (46%)
C2H2 Zn finger 406..426 CDD:275368 4/19 (21%)
C2H2 Zn finger 434..454 CDD:275368 3/19 (16%)
C2H2 Zn finger 462..483 CDD:275368 7/20 (35%)
C2H2 Zn finger 491..511 CDD:275368 0/19 (0%)
C2H2 Zn finger 519..539 CDD:275368 7/19 (37%)
C2H2 Zn finger 652..673 CDD:275368
C2H2 Zn finger 681..701 CDD:275368
zf-H2C2_2 694..718 CDD:290200
C2H2 Zn finger 709..729 CDD:275368
tolA_full 724..>814 CDD:274303
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24388
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.