DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG13123

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_609315.1	Gene:	CG13123 / 34303	FlyBaseID:	FBgn0032150	Length:	323	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	76/348 - (21%)
Similarity:	129/348 - (37%)	Gaps:	110/348 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KVCRTCGKRTNAERSLNIFEKR-----NQTTLEHIKLLTG--AVLKNCSTLPNRLCASC-QTCLQ 60
            |:||.|...:   .|::|.|.|     :||.|:.|:.:.|  ..|.....|| .:|..| :.|||
  Fly     5 KLCRICFVDS---ASVDIREHRSGGSSDQTVLQLIEAMFGWNIALNLTEELP-MICNDCLEDCLQ 65

  Fly    61 QAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQ 125
            |...||:... ..::||...::.: :.:||....:..|:.|     .:.|.|.|.|::....|
  Fly    66 QYAFFRKLTF-ANQQLLQLYNEAE-VEMCQVKMDATEEEPE-----NQASDEFEILEEFRRIP-- 121

  Fly   126 SSGFKVEDILNESKINEDEPN--------------------NED-----------------DIDY 153
                     |:...::.|.|.                    |:|                 |:..
  Fly   122 ---------LDYVVLDPDRPTETRQTRRRTDSCTKPSQRLANQDSLIVSEFLPATTAQPRLDLSD 177

  Fly   154 SEMDYL---IYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHC 215
            |:::.|   .||..|...|..||        |..|.....::||....|..|:.
  Fly   178 SQLEQLESPAYEMRTVDYAAVEL--------KHYNLDEYNEANRLLDVEPSGSQ----------- 223

  Fly   216 KRHRGVKEFGCEFCEDRFCTPAELKRHIR-KHTGEKPFKCRHCSRSFS---DYSTRLKHERTHTN 276
                  ..:.|::|...:.:|..||.|:| .|.      |::|:.:|:   |.:..::.:..|..
  Fly   224 ------AIYKCQYCPLAYASPQYLKTHVRNSHV------CKYCTTAFAKVRDLNEHIRQKHPHHQ 276

  Fly   277 ERPFVCKECNNAFTTSYILKNHM 299
                 |..|:|.|:||..|:.|:
  Fly   277 -----CVVCSNNFSTSSNLRAHL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	23/79 (29%)
		C2H2 Zn finger	198..218	CDD:275368	2/19 (11%)
		COG5048	222..>276	CDD:227381	13/57 (23%)
		C2H2 Zn finger	226..246	CDD:275368	7/20 (35%)
		zf-H2C2_2	238..262	CDD:290200	7/24 (29%)
		C2H2 Zn finger	254..274	CDD:275368	4/22 (18%)
		zf-H2C2_2	269..291	CDD:290200	5/21 (24%)
		C2H2 Zn finger	282..302	CDD:275368	8/18 (44%)
		zf-H2C2_2	295..319	CDD:290200	2/5 (40%)
		C2H2 Zn finger	310..328	CDD:275368
CG13123	NP_609315.1	zf-AD	6..82	CDD:285071	24/80 (30%)
		PHA00733	175..272	CDD:177301	26/127 (20%)
		C2H2 Zn finger	228..245	CDD:275368	5/16 (31%)
		C2H2 Zn finger	251..272	CDD:275368	4/20 (20%)
		C2H2 Zn finger	277..298	CDD:275368	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000