DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG15436

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	91/340 - (26%)
Similarity:	140/340 - (41%)	Gaps:	87/340 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KVCRTC----GKRTNAERSLNIFEKRNQTTL---EHIKLLTGAVLKNCSTLPNRLCASCQTCLQQ 61
            ::||.|    ||      .:|||:.|.:|.:   |.|...||..:|........:|..|...::.
  Fly     3 EICRVCMDISGK------LVNIFDARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKS 61

  Fly    62 AISFRERCLEVQRELLHSQDD--EDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPI 124
            |...|:.|.|..:.....:|:  ||.|  |     ::||:|:.|
  Fly    62 AYGIRQTCEESHQFYCRVRDEGIEDAL--C-----ALLEEEDWE--------------------- 98

  Fly   125 QSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNP 189
                           |:|||                   |..:|:......|.::..|:
  Fly    99 ---------------ISEDE-------------------DARIDSASAADDDGKSDSKK------ 123

  Fly   190 RDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKC 254
                ..|.|.||....:.:.:|:.|.:.|...:.|.|.:|:..|.....||.|::.|...||::|
  Fly   124 ----VAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYEC 184

  Fly   255 RHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSR 319
            .||:::|:..||...||||||.||||.|.:|:..|..|..|:.|:..|..|:.|:|..|.|.|:|
  Fly   185 SHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTR 249

  Fly   320 YTHLTTHYRSNAHRR 334
            ..||..|:||:...|
  Fly   250 KFHLDNHFRSHTGER 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	21/78 (27%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	9/23 (39%)
		C2H2 Zn finger	254..274	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..291	CDD:290200	13/21 (62%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	9/23 (39%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	21/79 (27%)
		C2H2 Zn finger	128..148	CDD:275368	5/19 (26%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	38/85 (45%)
		C2H2 Zn finger	184..204	CDD:275368	9/19 (47%)
		zf-H2C2_2	197..219	CDD:290200	12/21 (57%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		zf-H2C2_2	224..249	CDD:290200	9/24 (38%)
		C2H2 Zn finger	240..260	CDD:275368	9/19 (47%)
		zf-H2C2_2	252..276	CDD:290200	6/13 (46%)
		C2H2 Zn finger	268..288	CDD:275368
		C2H2 Zn finger	296..316	CDD:275368
		C2H2 Zn finger	324..341	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960