DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and AgaP_AGAP011405

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_554837.3	Gene:	AgaP_AGAP011405 / 3291310	VectorBaseID:	AGAP011405	Length:	438	Species:	Anopheles gambiae

Alignment Length:	420	Identity:	99/420 - (23%)
Similarity:	161/420 - (38%)	Gaps:	101/420 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VCRTCGKR-TNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRER 68
            :||.|..| .|....:.|... :..|||.|...||.:|........|:|.:|...|:|:..||:.
Mosquito    12 ICRFCLCRDDNCLVPVKILTD-SSITLEEIDHFTGILLDTDEDSTVRVCVNCIIKLKQSAEFRKA 75

  Fly    69 CL--EVQRELLH---SQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSG 128
            |:  :|..:.||   :...|..:....::|      :.::.|.|:..:..|..||:.....:||.
Mosquito    76 CISKDVLFQQLHVLVASTGEPEVDTPTDTP------DNIDSDSAKQQVSDEPYDDIGNLEDESSD 134

  Fly   129 FKVEDILNE---------------SKINE--------DEPNNEDDIDYSEMDYLI-------YES 163
            :..|:.:.|               |:::|        |||..||...:...:|::       .||
Mosquito   135 YLEEEFIVEVIQHGNEELDNANVVSELHEKQQEEFSIDEPVTEDTDFFYSANYIVPGDPSLSDES 199

  Fly   164 DTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECG-----------NHIK----------- 206
            :...|...|.::.|..|.:.|.|..|:...|.:.|:.||           ||.|
Mosquito   200 EIGEDGVNEEQASSPRPTETRARTRPKKKQRKYLCDTCGVLINDLPRHTLNHSKLIKHACPHCPV 264

  Fly   207 -----------------DRI---------------SFILHCKRHRGVKE-FGCEFCEDRFCTPAE 238
                             .||               |.:.|...|.|:.: ..|:.|...|...:.
Mosquito   265 EMVEYSNLLRHIEAVHEKRIRKSCELCGKGFTHNNSLVSHMVVHHGIGDTHKCKVCPKVFRHASG 329

  Fly   239 LKRHIRK-HTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVH 302
            |:.|::| |:....|:|..|...||......||.|:|::|||:.|.||...|.:.|..:.|...|
Mosquito   330 LRGHVKKCHSNATKFECSLCGAFFSSRYDLKKHGRSHSSERPYECSECGKRFKSQYARRIHEQAH 394

  Fly   303 TGEKAFRCDLCDKLFSRYTHLTTHYRSNAH 332
            :| ..:.||:|.:.: ||..|...:....|
Mosquito   395 SG-LLYECDVCRRPY-RYKALMRMHMKRTH 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	22/74 (30%)
		C2H2 Zn finger	198..218	CDD:275368	10/73 (14%)
		COG5048	222..>276	CDD:227381	16/55 (29%)
		C2H2 Zn finger	226..246	CDD:275368	6/20 (30%)
		zf-H2C2_2	238..262	CDD:290200	7/24 (29%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	6/23 (26%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
AgaP_AGAP011405	XP_554837.3	zf-AD	12..86	CDD:285071	22/74 (30%)
		C2H2 Zn finger	259..280	CDD:275370	0/20 (0%)
		C2H2 Zn finger	288..308	CDD:275370	2/19 (11%)
		C2H2 Zn finger	317..338	CDD:275368	6/20 (30%)
		C2H2 Zn finger	346..366	CDD:275368	7/19 (37%)
		zf-H2C2_2	358..383	CDD:290200	11/24 (46%)
		C2H2 Zn finger	374..394	CDD:275368	6/19 (32%)
		C2H2 Zn finger	401..422	CDD:275368	6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26093
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010