DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG31441

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	109/347 - (31%)
Similarity:	187/347 - (53%)	Gaps:	27/347 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VCRTCGKR-TNAE-RSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRE 67
            :||||||. ||.: |:..:|.|.|...:..::.:|...|:..:|||:.:|..|:..|.:.::||.
  Fly     7 ICRTCGKNVTNLQGRATKLFNKSNYHFISILENITDMYLEFDTTLPHLICQCCKVQLDRILTFRN 71

  Fly    68 RCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERL-DDLNEGPIQSSGFKV 131
            :||||.:..:.:  :...||      |..:..|||:      ..:||:| .||.:...|.....:
  Fly    72 KCLEVHKSFMAA--NRKLLR------KKAIVDEELD------KPDVEKLQQDLWDHTDQEMCVAM 122

  Fly   132 ED---ILNESKINEDEPNNEDDIDYSE--MDYLIYESDTEVDAKQE----LKSDSENPKKRRNRR 187
            .|   :|.|...:.::..:.:|...:|  .:..:.....||:..||    :...|:....|..:|
  Fly   123 ADTAGLLREDHNDNEKAKDAEDATQNEKNQEEQVQVQTEEVEHCQEQLHNMSIISKGVSARVPKR 187

  Fly   188 NPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPF 252
            ..|:| :::||::||...|......||.:||.|.|.|.|:.|:.::.|..|::||...||..:|:
  Fly   188 TKRNS-KSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRHRILHTDARPY 251

  Fly   253 KCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLF 317
            .||.||:::...|:::.|||||||||||.|:.|:.|||::...:.|.::||.::.:.|::||:.|
  Fly   252 ACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEMLHTNQRKYHCEICDQWF 316

  Fly   318 SRYTHLTTHYRSNAHRRNMQKA 339
            .|.:|||.|..:..|:|..:.|
  Fly   317 LRSSHLTLHQSTKLHQRRAESA 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	26/73 (36%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	10/23 (43%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	15/21 (71%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	7/23 (30%)
		C2H2 Zn finger	310..328	CDD:275368	9/17 (53%)
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	26/74 (35%)
		COG5048	<174..337	CDD:227381	61/163 (37%)
		C2H2 Zn finger	197..217	CDD:275370	6/19 (32%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		zf-H2C2_2	268..290	CDD:290200	15/21 (71%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	309..328	CDD:275368	9/18 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950