DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and Zfp819

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001014039.1	Gene:	Zfp819 / 308561	RGDID:	1309564	Length:	614	Species:	Rattus norvegicus

Alignment Length:	350	Identity:	88/350 - (25%)
Similarity:	141/350 - (40%)	Gaps:	76/350 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCLEVQRE 75
            :|...|::|   :...||..||        ..:.:..||.:..||:.|.|...|  ..|
  Rat   194 RRCPCEKTL---QPNLQTDSEH--------QSSATKQPNGVVDSCRLCTQGLSS--AVC------ 239

  Fly    76 LLHSQDDEDFLRICQE-------SPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVED 133
            ..||..:    |.|..       ||:|.|.|..:   |::            :.|::.:  |.|.
  Rat   240 TTHSTGE----RACTGNQCANVLSPRSPLRQHGI---LSQ------------DEPVEYT--KDEK 283

  Fly   134 ILNESKIN-EDEPNNEDDIDYSEMDYLIYES----------------DTEVDAKQELKSDSENPK 181
            .......: |.:..|..|::...:.::..:|                :|..:....|||.:.:|.
  Rat   284 AFTAGSASCEQQTTNTLDLETHFICHICGKSFLQKSELSFHPGTSREETRYECPDCLKSLTTSPS 348

  Fly   182 KRRNRRNPRDSNRTFFCEECG------NHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELK 240
            ..:.........:.:.|.:||      :|:|      :|.:.|.|.:.:.|..|...|...:.|.
  Rat   349 SLQAHHEAHTKQKPYTCHDCGKSFSYASHLK------VHLRIHTGERPYVCSDCGKAFSQKSVLT 407

  Fly   241 RHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGE 305
            .|.|.||||||:.|.||.:.|...|...||.|.||.|:|:.|::|...|:....|..|..:||||
  Rat   408 THQRIHTGEKPYACSHCGKLFVYASDLRKHSRFHTGEKPYECRDCGKVFSNKSHLPVHRRIHTGE 472

  Fly   306 KAFRCDLCDKLFSRYTHLTTHYRSN 330
            |.::|..|.|.|.|.:||..|.|::
  Rat   473 KPYKCRDCGKSFRRKSHLQVHGRTH 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	15/65 (23%)
		C2H2 Zn finger	198..218	CDD:275368	6/25 (24%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	5/19 (26%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
Zfp819	NP_001014039.1	KRAB	27..81	CDD:214630
		C2H2 Zn finger	336..357	CDD:275368	4/20 (20%)
		COG5048	<346..538	CDD:227381	52/157 (33%)
		C2H2 Zn finger	365..385	CDD:275368	6/25 (24%)
		C2H2 Zn finger	393..413	CDD:275368	6/19 (32%)
		C2H2 Zn finger	421..441	CDD:275368	8/19 (42%)
		C2H2 Zn finger	449..469	CDD:275368	5/19 (26%)
		C2H2 Zn finger	477..497	CDD:275368	9/19 (47%)
		SFP1	<499..582	CDD:227516
		C2H2 Zn finger	505..525	CDD:275368
		C2H2 Zn finger	533..553	CDD:275368
		C2H2 Zn finger	561..581	CDD:275368
		zf-H2C2_2	573..598	CDD:404364
		C2H2 Zn finger	589..609	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000