DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and Zfp281

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001012030.1	Gene:	Zfp281 / 305083	RGDID:	1305139	Length:	889	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	60/206 - (29%)
Similarity:	90/206 - (43%)	Gaps:	37/206 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 IQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRN 188
            :.|||.:.:|..||      ||                :.||.|...:..|.:|:..|.   :|.
  Rat   191 LSSSGSRTDDHGNE------EP----------------KQDTNVKKAKRPKPESQGIKA---KRK 230

  Fly   189 PRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFK 253
            |..|::....|..|..:..            ..|...|:.|...|.:...|:||:..||||:||:
  Rat   231 PSASSKPLVGEGEGAVLSP------------SQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQ 283

  Fly   254 CRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFS 318
            |..||..|.......:||:.|:.|:||.|.:|:..|...|.::.|...|:|||.::||.|.:.||
  Rat   284 CSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFS 348

  Fly   319 RYTHLTTHYRS 329
            |...|..|.|:
  Rat   349 RTDRLLKHRRT 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	2/19 (11%)
		COG5048	222..>276	CDD:227381	20/53 (38%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	9/21 (43%)
		C2H2 Zn finger	282..302	CDD:275368	5/19 (26%)
		zf-H2C2_2	295..319	CDD:290200	9/23 (39%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
Zfp281	NP_001012030.1	zf-C2H2_4	254..276	CDD:404733	6/21 (29%)
		C2H2 Zn finger	256..276	CDD:275368	6/19 (32%)
		zf-H2C2_2	268..293	CDD:404364	13/24 (54%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		C2H2 Zn finger	312..332	CDD:275368	5/19 (26%)
		zf-H2C2_2	324..349	CDD:404364	9/24 (38%)
		C2H2 Zn finger	340..359	CDD:275368	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910