DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and ace2

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_594109.1	Gene:	ace2 / 2541661	PomBaseID:	SPAC6G10.12c	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	257	Identity:	57/257 - (22%)
Similarity:	95/257 - (36%)	Gaps:	69/257 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDI 134
            |:|.|   |:.:.:.|.::  .||             ||...|.|:...:.:..:..|...:.:.
pombe   303 LDVCR---HTDNQKAFAKL--SSP-------------AEYVSEFEKFSSVCDHGLDISNANINNT 349

  Fly   135 LN---------ESKINEDEPNNEDDIDYSEMDYL---IYESD-------TEVDAKQELKSDSENP 180
            |.         ||.|...:|  |..|...|.:.|   |..:|       ||.|:|..::...::.
pombe   350 LTQQFALSAPYESCIVTKKP--EPCITVKEEEQLAPKIESADLSITPQVTEHDSKPPVRISYDHR 412

  Fly   181 KKRRNR-----RNPRDSNRTFFC--EECGNHIKDRISFILHCKRHRGVKEFGCEF--CEDRFCTP 236
            .|.|.:     |.|.::..:.:|  |..|.::                    |.:  |..|....
pombe   413 CKTRKQSTRICRIPPETMASLYCGPEADGKYV--------------------CLYNGCNKRIARK 457

  Fly   237 AELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNH 298
            ..::.||:.|..::|::|..|...|..:....:|.|.|.|.||:|| ||...|.....|..|
pombe   458 YNVESHIQTHLSDRPYRCDLCKAGFVRHHDLKRHLRIHENGRPYVC-ECLKRFNRLDALNRH 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	3/6 (50%)
		C2H2 Zn finger	198..218	CDD:275368	3/21 (14%)
		COG5048	222..>276	CDD:227381	13/55 (24%)
		C2H2 Zn finger	226..246	CDD:275368	5/21 (24%)
		zf-H2C2_2	238..262	CDD:290200	6/23 (26%)
		C2H2 Zn finger	254..274	CDD:275368	5/19 (26%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	6/17 (35%)
		zf-H2C2_2	295..319	CDD:290200	2/4 (50%)
		C2H2 Zn finger	310..328	CDD:275368
ace2	NP_594109.1	COG5048	45..518	CDD:227381	56/255 (22%)
		C2H2 Zn finger	448..467	CDD:275368	4/18 (22%)
		zf-C2H2	473..495	CDD:278523	5/21 (24%)
		C2H2 Zn finger	475..495	CDD:275368	5/19 (26%)
		zf-H2C2_2	487..511	CDD:290200	11/24 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050