DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ranshi and Zbtb6

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_666365.1	Gene:	Zbtb6 / 241322	MGIID:	2442998	Length:	423	Species:	Mus musculus

Alignment Length:	353	Identity:	87/353 - (24%)
Similarity:	141/353 - (39%)	Gaps:	90/353 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 EHIKLLTGA-------VLKNCS-----------TLPNR----LCASCQTCLQQAISFRERCLEVQ 73
            |.:|.||.|       :::.|:           ::.|.    ||.|..|             :|:
Mouse    99 ELLKYLTAASYLQMVHIVEKCTEALSKYLEIDLSMKNNQHTDLCQSSDT-------------DVK 150

  Fly    74 RELLHSQDDEDFLRICQESPKS----VLEQEELELDLAEISIEVERLDDLNEGPIQSS---GFKV 131
            .|..:|..|.:.:.|.::||.:    |.|:|...|..|..::..||:  ..:.|..|:   |||.
Mouse   151 NEEENSDKDCEIIEISEDSPVNLDFHVKEEESNALQSAAETLTSERM--RMQSPELSAVDGGFKE 213

  Fly   132 EDILNESKINEDEPNNEDDIDYSEMDYL-------IYESDTEVDAKQELKSDSENPKKRRNRRNP 189
                ||..|...|..:.||::..:....       ||..:|:   ...:.|..||    |....|
Mouse   214 ----NEICILHVESISTDDVENGQFSQPCTSSKAGIYFPETQ---HSLINSTVEN----RVTEVP 267

  Fly   190 RDSNRTFFCEEC-GNH--------IKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRK 245
            .::|:..|.|.. |:|        :.:..|.     ||:      |..|...|.......||::.
Mouse   268 GNTNQGLFSENSDGSHGTVNEIQNLDENFSL-----RHQ------CPRCPRGFLHVENYLRHLKM 321

  Fly   246 HTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRC 310
            |   |.|.|..|.::|:......:|.|.|...|||.|..|...||....|::|:.:|:|::.::|
Mouse   322 H---KLFLCLQCGKTFTQKKNLNRHIRGHMGIRPFQCTVCLKTFTAKSTLQDHLNIHSGDRPYKC 383

  Fly   311 DLCDKLFSRYT----HLTT-HYRSNAHR 333
            ..||..|...:    |||: |.||:..:
Mouse   384 HCCDMDFKHKSALKKHLTSVHGRSSGEK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	13/67 (19%)
		C2H2 Zn finger	198..218	CDD:275368	4/28 (14%)
		COG5048	222..>276	CDD:227381	14/53 (26%)
		C2H2 Zn finger	226..246	CDD:275368	5/19 (26%)
		zf-H2C2_2	238..262	CDD:290200	7/23 (30%)
		C2H2 Zn finger	254..274	CDD:275368	5/19 (26%)
		zf-H2C2_2	269..291	CDD:290200	9/21 (43%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	8/23 (35%)
		C2H2 Zn finger	310..328	CDD:275368	8/22 (36%)
Zbtb6	NP_666365.1	BTB	23..123	CDD:279045	6/23 (26%)
		BTB	34..127	CDD:197585	6/27 (22%)
		C2H2 Zn finger	302..322	CDD:275368	5/19 (26%)
		zf-C2H2	325..347	CDD:278523	6/21 (29%)
		C2H2 Zn finger	327..347	CDD:275368	5/19 (26%)
		zf-H2C2_2	339..363	CDD:290200	8/23 (35%)
		C2H2 Zn finger	355..375	CDD:275368	6/19 (32%)
		C2H2 Zn finger	383..400	CDD:275368	4/16 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000