DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and Zbtb16

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001028496.1	Gene:	Zbtb16 / 235320	MGIID:	103222	Length:	673	Species:	Mus musculus

Alignment Length:	146	Identity:	53/146 - (36%)
Similarity:	76/146 - (52%)	Gaps:	4/146 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 NRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGE 249
            :|:....::...||..||...:.:.:...|.:.|.||:.:.|..|...|.:...||||:|.|||:
Mouse   479 HRQTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHTGD 543

  Fly   250 KPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCD 314
            .|::|..|...|.|.||...|:|.||.|:|:.|..|...|:..:.|:.|..||||||.|.|.||.
Mouse   544 HPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCH 608

  Fly   315 KLFSRYT----HLTTH 326
            :....|:    ||.||
Mouse   609 QRSRDYSAMIKHLRTH 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	8/19 (42%)
		zf-H2C2_2	238..262	CDD:290200	11/23 (48%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	9/21 (43%)
		C2H2 Zn finger	282..302	CDD:275368	5/19 (26%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	8/21 (38%)
Zbtb16	NP_001028496.1	BTB_POZ_ZBTB16_PLZF	16..122	CDD:349514
		C2H2 Zn finger	406..426	CDD:275368
		C2H2 Zn finger	434..454	CDD:275368
		COG5048	<448..622	CDD:227381	50/142 (35%)
		C2H2 Zn finger	463..483	CDD:275368	1/3 (33%)
		C2H2 Zn finger	492..512	CDD:275368	4/19 (21%)
		C2H2 Zn finger	520..540	CDD:275368	8/19 (42%)
		C2H2 Zn finger	548..568	CDD:275368	8/19 (42%)
		C2H2 Zn finger	576..596	CDD:275368	5/19 (26%)
		C2H2 Zn finger	604..624	CDD:275368	6/19 (32%)
		C2H2 Zn finger	632..652	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910