DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and Zfp62

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001349654.1	Gene:	Zfp62 / 22720	MGIID:	99662	Length:	914	Species:	Mus musculus

Alignment Length:	347	Identity:	94/347 - (27%)
Similarity:	136/347 - (39%)	Gaps:	48/347 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKL-LTGAVLKNCSTL-------PNRLCASCQTCLQQA 62
            |..|||.......| |..||..|..:..|. :.|......|.|       |.:....|:.|   .
Mouse   357 CDECGKAFRNSSGL-IVHKRIHTGEKPYKCDICGKAFSYSSGLAVHKSIHPGKKAHECKDC---G 417

  Fly    63 ISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSS 127
            .||....|.:|.:.:|:.:......:|.::.::            ...::|.|.....|.|.:.
Mouse   418 KSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRN------------NSGLKVHRRLHTGEKPYKC- 469

  Fly   128 GFKVEDILNESKINEDEPNNEDDIDYSEMDY--------LIYESDTE----VDAKQELKSDSENP 180
                 |:..::.|:.....|...|...|..|        ..|.|..|    :..:::.....|..
Mouse   470 -----DVCGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECG 529

  Fly   181 KKRRN------RRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAEL 239
            |..||      .:......|.:.|||||.......|.|.|...|.|.|.|.|:.||..|.|...|
Mouse   530 KAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTL 594

  Fly   240 KRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTG 304
            ..|.:.|.||||:||..|.:||:..|...:|:|.||.|:||.|..|...|..:..||.|..:|||
Mouse   595 LNHKKIHLGEKPYKCDVCEKSFNYTSLLSQHKRVHTREKPFECDRCEKVFRNNSSLKVHKRIHTG 659

  Fly   305 EKAFRCDLCDKLFSRYTHLTTH 326
            ||.:.||:|.|.:..::.|..|
Mouse   660 EKPYECDICGKAYISHSSLINH 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	20/78 (26%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		COG5048	222..>276	CDD:227381	23/53 (43%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	11/23 (48%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
Zfp62	NP_001349654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..101
		COG5048	127..542	CDD:227381	39/206 (19%)
		C2H2 Zn finger	133..153	CDD:275368
		C2H2 Zn finger	161..181	CDD:275368
		C2H2 Zn finger	189..209	CDD:275368
		C2H2 Zn finger	217..237	CDD:275368
		C2H2 Zn finger	245..265	CDD:275368
		C2H2 Zn finger	273..293	CDD:275368
		C2H2 Zn finger	301..321	CDD:275368
		C2H2 Zn finger	329..349	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368	8/20 (40%)
		SFP1	<379..458	CDD:227516	14/93 (15%)
		C2H2 Zn finger	385..405	CDD:275368	3/19 (16%)
		C2H2 Zn finger	413..433	CDD:275368	6/22 (27%)
		COG5048	437..850	CDD:227381	73/263 (28%)
		C2H2 Zn finger	441..461	CDD:275368	3/31 (10%)
		C2H2 Zn finger	469..489	CDD:275368	3/25 (12%)
		C2H2 Zn finger	497..517	CDD:275368	3/19 (16%)
		C2H2 Zn finger	525..545	CDD:275368	4/19 (21%)
		C2H2 Zn finger	553..573	CDD:275368	8/19 (42%)
		C2H2 Zn finger	581..601	CDD:275368	7/19 (37%)
		C2H2 Zn finger	609..629	CDD:275368	7/19 (37%)
		C2H2 Zn finger	637..657	CDD:275368	6/19 (32%)
		C2H2 Zn finger	665..685	CDD:275368	6/17 (35%)
		C2H2 Zn finger	693..713	CDD:275368
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
		C2H2 Zn finger	777..797	CDD:275368
		C2H2 Zn finger	805..824	CDD:275368
		C2H2 Zn finger	832..852	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000