DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and Zfp281

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001153723.1	Gene:	Zfp281 / 226442	MGIID:	3029290	Length:	893	Species:	Mus musculus

Alignment Length:	217	Identity:	60/217 - (27%)
Similarity:	94/217 - (43%)	Gaps:	26/217 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 VERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDS 177
            ::.|..|::...|.......|:|..|....||..|::.           :.|..|...:..|.:|
Mouse   173 IQDLSLLHQHAQQQPAQHHRDVLLSSGSRTDEHGNQEP-----------KQDANVKKAKRPKPES 226

  Fly   178 ENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRH 242
            :..|.   :|.|..|::....|..|..:..            ..|...|:.|...|.:...|:||
Mouse   227 QGIKA---KRKPSASSKPLVGEGEGAVLSP------------SQKPHICDHCSAAFRSSYHLRRH 276

  Fly   243 IRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKA 307
            :..||||:||:|..||..|.......:||:.|:.|:||.|.:|:..|...|.::.|...|:|||.
Mouse   277 VLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKP 341

  Fly   308 FRCDLCDKLFSRYTHLTTHYRS 329
            ::||.|.:.|||...|..|.|:
Mouse   342 YKCDTCQQYFSRTDRLLKHRRT 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	2/19 (11%)
		COG5048	222..>276	CDD:227381	20/53 (38%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	9/21 (43%)
		C2H2 Zn finger	282..302	CDD:275368	5/19 (26%)
		zf-H2C2_2	295..319	CDD:290200	9/23 (39%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
Zfp281	NP_001153723.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..113
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	126..148
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	153..172
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..251		14/66 (21%)
		zf-C2H2	258..280	CDD:278523	6/21 (29%)
		C2H2 Zn finger	260..280	CDD:275368	6/19 (32%)
		zf-H2C2_2	272..297	CDD:290200	13/24 (54%)
		C2H2 Zn finger	288..308	CDD:275368	6/19 (32%)
		zf-H2C2_2	301..325	CDD:290200	9/23 (39%)
		C2H2 Zn finger	316..336	CDD:275368	5/19 (26%)
		zf-H2C2_2	328..353	CDD:290200	9/24 (38%)
		C2H2 Zn finger	344..363	CDD:275368	8/18 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	371..425
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	613..658
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	775..815
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910