DRSC/TRiP Functional Genomics Resources

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Protein Alignment ranshi and ZSCAN25

DIOPT Version :9

Sequence 1:NP_649824.1 Gene:ranshi / 41041 FlyBaseID:FBgn0037620 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_001337908.1 Gene:ZSCAN25 / 221785 HGNCID:21961 Length:544 Species:Homo sapiens


Alignment Length:277 Identity:74/277 - (26%)
Similarity:114/277 - (41%) Gaps:50/277 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 ELLHSQDDEDFLRICQESPKSVLEQEEL-----ELDLAEISIEVERLDDLNEGPIQSSGFKVEDI 134
            |.:..||       |:.||....:::|.     :|..|.:::..||   ..|..:|..|.     
Human   257 EYVEPQD-------CRVSPGGGSKEKEAKPPQEDLKGALVALTSER---FGEASLQGPGL----- 306

  Fly   135 LNESKINEDEPNN------------------EDDIDYSEMDYLIYESDTEVDAKQELKSDSENPK 181
               .::.|.||..                  .|::......:..::      ..:..|..|.:..
Human   307 ---GRVCEQEPGGPAGSAPGLPPPQHGAIPLPDEVKTHSSFWKPFQ------CPECGKGFSRSSN 362

  Fly   182 KRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKH 246
            ..|::|...:  :::.|.|||.....|...:.|.:.|.|.:.:.|..|...|.....|:.|.|.|
Human   363 LVRHQRTHEE--KSYGCVECGKGFTLREYLMKHQRTHLGKRPYVCSECWKTFSQRHHLEVHQRSH 425

  Fly   247 TGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCD 311
            |||||:||..|.:|||.......|.||||.|:|:.| ||..:|:.:..|..|...|||||.:.|.
Human   426 TGEKPYKCGDCWKSFSRRQHLQVHRRTHTGEKPYTC-ECGKSFSRNANLAVHRRAHTGEKPYGCQ 489

  Fly   312 LCDKLFSRYTHLTTHYR 328
            :|.|.||:...|..|.|
Human   490 VCGKRFSKGERLVRHQR 506

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ranshiNP_649824.1 zf-AD 5..77 CDD:214871 1/1 (100%)
C2H2 Zn finger 198..218 CDD:275368 6/19 (32%)
COG5048 222..>276 CDD:227381 22/53 (42%)
C2H2 Zn finger 226..246 CDD:275368 6/19 (32%)
zf-H2C2_2 238..262 CDD:290200 13/23 (57%)
C2H2 Zn finger 254..274 CDD:275368 7/19 (37%)
zf-H2C2_2 269..291 CDD:290200 11/21 (52%)
C2H2 Zn finger 282..302 CDD:275368 6/19 (32%)
zf-H2C2_2 295..319 CDD:290200 11/23 (48%)
C2H2 Zn finger 310..328 CDD:275368 7/17 (41%)
ZSCAN25NP_001337908.1 SCAN 38..136 CDD:322011
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 157..189
KRAB_A-box 231..>259 CDD:143639 1/1 (100%)
COG5048 <324..532 CDD:227381 57/192 (30%)
C2H2 Zn finger 350..370 CDD:275368 4/19 (21%)
C2H2 Zn finger 377..397 CDD:275368 6/19 (32%)
C2H2 Zn finger 405..425 CDD:275368 6/19 (32%)
C2H2 Zn finger 433..453 CDD:275368 7/19 (37%)
C2H2 Zn finger 461..480 CDD:275368 6/19 (32%)
C2H2 Zn finger 488..508 CDD:275368 8/19 (42%)
C2H2 Zn finger 516..535 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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