DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ranshi and M03D4.4

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	190	Identity:	54/190 - (28%)
Similarity:	85/190 - (44%)	Gaps:	9/190 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 NEDEPNNEDDIDYSEMDYL-IYESD--TEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECG 202
            :::|...|||.|...|..: |.:||  ::.|:.|.    |.||.....:.:..:..| :.||:|.
Worm    35 DQEEDRMEDDSDELAMIKIKIEDSDFLSDTDSSQL----SMNPTTPSEKSSSGEKGR-YECEDCH 94

  Fly   203 NHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTR 267
            .....:.....|.:.|.|.:...|..|...|.|...||:|...||||:...|.||:::|......
Worm    95 EMFAVKRELATHMRIHSGEQPHSCTQCGKEFGTRQLLKKHWMWHTGERSHVCPHCNKAFFQKGHL 159

  Fly   268 LKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHY 327
            .:|...|:..||..|.:|:..|...:.|..||.:|. |:.|.|..|.:.|.:...|..|:
Worm   160 TQHLMIHSGGRPHECPQCHKTFIFKFDLNRHMKIHQ-ERGFSCQQCGRSFLKQVMLDEHH 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	17/53 (32%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	10/23 (43%)
		C2H2 Zn finger	254..274	CDD:275368	5/19 (26%)
		zf-H2C2_2	269..291	CDD:290200	7/21 (33%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	9/23 (39%)
		C2H2 Zn finger	310..328	CDD:275368	5/18 (28%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	4/19 (21%)
		zf-H2C2_2	102..127	CDD:290200	6/24 (25%)
		C2H2 Zn finger	118..138	CDD:275368	7/19 (37%)
		C2H2 Zn finger	146..166	CDD:275368	5/19 (26%)
		zf-H2C2_2	158..181	CDD:290200	6/22 (27%)
		zf-C2H2	172..194	CDD:278523	6/21 (29%)
		C2H2 Zn finger	174..194	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000