Protein Alignment ranshi and ZNF540

DIOPT Version :9

• Sequence 1: NP_649824.1
• Gene: ranshi / 41041
• FlyBaseID: FBgn0037620
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_001165696.1
• Gene: ZNF540 / 163255
• HGNCID: 25331
• Length: 660
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 90/338 - (26%)
• Similarity: 134/338 - (39%)
• Gaps: 78/338 - (23%)

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCA-----------SCQTCL 59
            |:.|||..|....||    |::|....||.....|.:...:....|..           .|:.|
Human   385 CKECGKSFNVRGQLN----RHKTIHTGIKPFACKVCEKAFSYSGDLRVHSRIHTGEKPYECKEC- 444

  Fly    60 QQAISFRERCLEVQRELLHS--QDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEG 122
            .:|...|....|.||  ||:  :..|     |:|..|:...:.::.|. .:|..:|:....:..|
Human   445 GKAFMLRSVLTEHQR--LHTGVKPYE-----CKECGKTFRVRSQISLH-KKIHTDVKPYKCVRCG 501

  Fly   123 PIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRR 187
            .....||                            ||     ||   .|.:.: .|.|.|
Human   502 KTFRFGF----------------------------YL-----TE---HQRIHT-GEKPYK----- 524

  Fly   188 NPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPF 252
                      |:|||.....|.:...|.|.|.|:|.:.|:.|...|....:...|.:.|||.||:
Human   525 ----------CKECGKAFIRRGNLKEHLKIHSGLKPYDCKECGKSFSRRGQFTEHQKIHTGVKPY 579

  Fly   253 KCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLF 317
            ||:.|.::||.......|:|.||.|:|:.||:|..||..:..|..|..:|||||.:.|.:|.|.|
Human   580 KCKECGKAFSRSVDLRIHQRIHTGEKPYECKQCGKAFRLNSHLTEHQRIHTGEKPYECKVCRKAF 644

  Fly   318 SRYTHLTTHYRSN 330
            .:|:||..|.:::
Human   645 RQYSHLYQHQKTH 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	20/81 (25%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		COG5048	222..>276	CDD:227381	18/53 (34%)
		C2H2 Zn finger	226..246	CDD:275368	4/19 (21%)
		zf-H2C2_2	238..262	CDD:290200	9/23 (39%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
ZNF540	NP_001165696.1	KRAB	6..66	CDD:214630
		C2H2 Zn finger	189..209	CDD:275368
		C2H2 Zn finger	217..237	CDD:275368
		COG5048	241..620	CDD:227381	75/299 (25%)
		C2H2 Zn finger	245..265	CDD:275368
		C2H2 Zn finger	273..293	CDD:275368
		C2H2 Zn finger	301..321	CDD:275368
		C2H2 Zn finger	329..349	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368
		C2H2 Zn finger	385..405	CDD:275368	9/23 (39%)
		C2H2 Zn finger	413..433	CDD:275368	2/19 (11%)
		C2H2 Zn finger	441..461	CDD:275368	7/22 (32%)
		C2H2 Zn finger	469..489	CDD:275368	4/20 (20%)
		C2H2 Zn finger	497..517	CDD:275368	8/55 (15%)
		C2H2 Zn finger	525..545	CDD:275368	7/19 (37%)
		C2H2 Zn finger	553..573	CDD:275368	4/19 (21%)
		C2H2 Zn finger	581..601	CDD:275368	6/19 (32%)
		C2H2 Zn finger	609..629	CDD:275368	7/19 (37%)
		zf-H2C2_2	621..646	CDD:316026	11/24 (46%)
		C2H2 Zn finger	637..657	CDD:275368	8/19 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910