DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and ZNF582

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001307300.2	Gene:	ZNF582 / 147948	HGNCID:	26421	Length:	517	Species:	Homo sapiens

Alignment Length:	170	Identity:	59/170 - (34%)
Similarity:	97/170 - (57%)	Gaps:	3/170 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 IYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFI-LHCKRHRGVKE 223
            ::..:...:.|...|:.|.:.:...::|. ....:.:.|:|||... :|||.: :|.:.|.|.|.
Human   248 VHTGEKPYECKDCEKAFSRSSQLIEHQRT-HTGEKPYQCKECGKAF-NRISHLKVHYRIHTGEKP 310

  Fly   224 FGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNA 288
            :.|:.|...|...::|.:|...|||.|.::|:.|.::|:..||.::|:|.||.|:|:.||.|..|
Human   311 YACKECGKTFSHRSQLIQHQTVHTGRKLYECKECGKAFNQGSTLIRHQRIHTGEKPYECKVCGKA 375

  Fly   289 FTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYR 328
            |..|..||.|..:|||||.::|.:|.:.|.|.:|||.|||
Human   376 FRVSSQLKQHQRIHTGEKPYQCKVCGRAFKRVSHLTVHYR 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	8/20 (40%)
		COG5048	222..>276	CDD:227381	18/53 (34%)
		C2H2 Zn finger	226..246	CDD:275368	5/19 (26%)
		zf-H2C2_2	238..262	CDD:290200	8/23 (35%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	9/19 (47%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
ZNF582	NP_001307300.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910