DRSC/TRiP Functional Genomics Resources

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Protein Alignment ranshi and ZFP28

DIOPT Version :9

Sequence 1:NP_649824.1 Gene:ranshi / 41041 FlyBaseID:FBgn0037620 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_065879.1 Gene:ZFP28 / 140612 HGNCID:17801 Length:868 Species:Homo sapiens


Alignment Length:344 Identity:88/344 - (25%)
Similarity:137/344 - (39%) Gaps:53/344 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISF--RER 68
            |..|.|......||.:          |.::.||.....|:        .|........||  .:|
Human   422 CNECKKTFTQSSSLTV----------HQRIHTGEKPYKCN--------ECGKAFSDGSSFARHQR 468

  Fly    69 CLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQ----SSGF 129
            |...::..           .|.|..|:.::...|        |...|.....|.|..    ...|
Human   469 CHTGKKPY-----------ECIECGKAFIQNTSL--------IRHWRYYHTGEKPFDCIDCGKAF 514

  Fly   130 KVEDILNE-SKINEDEPNNEDDIDYSEMDY--------LIYESDTEVDAKQELKSDSENPKKRRN 185
            .....||: .:|:..|...:.|:.:....|        .|:..:...:.....|:.|.:....::
Human   515 SDHIGLNQHRRIHTGEKPYKCDVCHKSFRYGSSLTVHQRIHTGEKPYECDVCRKAFSHHASLTQH 579

  Fly   186 RRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEK 250
            :| .....:.|.|:|||...:..|....|.:.|.|.|.|.|..|...|...::|..|.|.|||||
Human   580 QR-VHSGEKPFKCKECGKAFRQNIHLASHLRIHTGEKPFECAECGKSFSISSQLATHQRIHTGEK 643

  Fly   251 PFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDK 315
            |::|:.||::|:..:...:|::|||.|:|:.||||..||:.:..|..|..||||||.::|..|.|
Human   644 PYECKVCSKAFTQKAHLAQHQKTHTGEKPYECKECGKAFSQTTHLIQHQRVHTGEKPYKCMECGK 708

  Fly   316 LFSRYTHLTTHYRSNAHRR 334
            .|...:..|.|.|.:..:|
Human   709 AFGDNSSCTQHQRLHTGQR 727

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ranshiNP_649824.1 zf-AD 5..77 CDD:214871 14/72 (19%)
C2H2 Zn finger 198..218 CDD:275368 6/19 (32%)
COG5048 222..>276 CDD:227381 21/53 (40%)
C2H2 Zn finger 226..246 CDD:275368 6/19 (32%)
zf-H2C2_2 238..262 CDD:290200 12/23 (52%)
C2H2 Zn finger 254..274 CDD:275368 5/19 (26%)
zf-H2C2_2 269..291 CDD:290200 12/21 (57%)
C2H2 Zn finger 282..302 CDD:275368 8/19 (42%)
zf-H2C2_2 295..319 CDD:290200 12/23 (52%)
C2H2 Zn finger 310..328 CDD:275368 6/17 (35%)
ZFP28NP_065879.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..82
KRAB 103..163 CDD:214630
KRAB 103..142 CDD:279668
KRAB 232..288 CDD:214630
KRAB 232..266 CDD:279668
COG5048 417..806 CDD:227381 88/344 (26%)
zf-C2H2 420..442 CDD:278523 6/29 (21%)
C2H2 Zn finger 422..442 CDD:275368 6/29 (21%)
zf-H2C2_2 434..458 CDD:290200 7/41 (17%)
C2H2 Zn finger 450..470 CDD:275368 5/27 (19%)
zf-H2C2_2 462..487 CDD:290200 7/35 (20%)
C2H2 Zn finger 478..496 CDD:275368 5/25 (20%)
C2H2 Zn finger 507..527 CDD:275368 3/19 (16%)
zf-H2C2_2 520..544 CDD:290200 5/23 (22%)
C2H2 Zn finger 535..555 CDD:275368 2/19 (11%)
zf-H2C2_2 547..572 CDD:290200 2/24 (8%)
C2H2 Zn finger 563..583 CDD:275368 3/20 (15%)
zf-H2C2_2 575..600 CDD:290200 6/25 (24%)
C2H2 Zn finger 591..611 CDD:275368 6/19 (32%)
zf-H2C2_2 603..627 CDD:290200 7/23 (30%)
C2H2 Zn finger 619..639 CDD:275368 6/19 (32%)
zf-H2C2_2 632..656 CDD:290200 13/23 (57%)
C2H2 Zn finger 647..667 CDD:275368 5/19 (26%)
zf-H2C2_2 659..684 CDD:290200 12/24 (50%)
C2H2 Zn finger 675..695 CDD:275368 8/19 (42%)
zf-H2C2_2 687..710 CDD:290200 11/22 (50%)
C2H2 Zn finger 703..723 CDD:275368 7/19 (37%)
zf-H2C2_2 718..740 CDD:290200 3/10 (30%)
C2H2 Zn finger 731..751 CDD:275368
zf-H2C2_2 743..768 CDD:290200
C2H2 Zn finger 759..779 CDD:275368
zf-H2C2_2 771..796 CDD:290200
C2H2 Zn finger 787..807 CDD:275368
C2H2 Zn finger 815..835 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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