DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and AgaP_AGAP003942

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_318400.2	Gene:	AgaP_AGAP003942 / 1278771	VectorBaseID:	AGAP003942	Length:	279	Species:	Anopheles gambiae

Alignment Length:	321	Identity:	77/321 - (23%)
Similarity:	107/321 - (33%)	Gaps:	97/321 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTC-GK-----------------RTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLC 52
            ||.| ||                 .|.:..|..:.||..:.|  :|||       :|:.  :..|
Mosquito    18 CRLCLGKESLLGVFATEKPLHNDGHTGSSSSTELVEKIYECT--NIKL-------SCTV--DAGC 71

  Fly    53 ASCQTCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLD 117
            |.|:.|||..                    :||......|.|        ..||.:::..|...|
Mosquito    72 AICRRCLQAV--------------------QDFYHFRVRSNK--------VNDLIQVTTVVANGD 108

  Fly   118 DLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVD------AKQELK-S 175
            |.|    .|||       ||:....            |...::..|.|...      |||:.| |
Mosquito   109 DDN----SSSG-------NEAPAKR------------ETTTVVVPSPTTTTTTPLPAAKQQPKPS 150

  Fly   176 DSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKR-HRGVKEFGCEFCEDRFCTPAEL 239
            ...|..|....|    |||   |..|....:.......|.|| |...::..|..|..:|.....|
Mosquito   151 IVSNASKTTGER----SNR---CRYCPKSFRTVAELAEHGKRTHVAGRQHHCPNCLAQFQHAPSL 208

  Fly   240 KRHIRKHT--GEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNH 298
            .||:|..:  ....::||.||.||.:......|.|.|..:.|:.|.:|.:.|.....|:.|
Mosquito   209 ARHMRSRSCFAFSKYRCRVCSESFPERDQWADHIRIHAKDFPYQCPDCWSQFKHKATLRRH 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	20/88 (23%)
		C2H2 Zn finger	198..218	CDD:275368	5/20 (25%)
		COG5048	222..>276	CDD:227381	16/55 (29%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	9/25 (36%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	7/21 (33%)
		C2H2 Zn finger	282..302	CDD:275368	5/17 (29%)
		zf-H2C2_2	295..319	CDD:290200	2/4 (50%)
		C2H2 Zn finger	310..328	CDD:275368
AgaP_AGAP003942	XP_318400.2	zf-AD	17..99	CDD:285071	26/119 (22%)
		zf-C2H2_2	166..240	CDD:289522	19/73 (26%)
		C2H2 Zn finger	166..187	CDD:275368	5/20 (25%)
		C2H2 Zn finger	195..215	CDD:275368	7/19 (37%)
		C2H2 Zn finger	225..245	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..269	CDD:275368	4/15 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000