DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and AgaP_AGAP005978

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_556655.3	Gene:	AgaP_AGAP005978 / 1276651	VectorBaseID:	AGAP005978	Length:	451	Species:	Anopheles gambiae

Alignment Length:	147	Identity:	49/147 - (33%)
Similarity:	80/147 - (54%)	Gaps:	2/147 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 RTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCS 258
            :.:.|..||.....:.:.:.|...|.|:|.:.|..|:..|...|.:.:|...|:|.||:||..|.
Mosquito   299 KPYKCNTCGKAFAQQANMVKHEMLHTGIKPYKCSVCDKAFAQQANMVKHQMLHSGIKPYKCPTCD 363

  Fly   259 RSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHL 323
            ::|:..:..:||:..||.|:||.||.|:.||:.:..||.|.:||.|.:...|.||.|.:|:|::|
Mosquito   364 KAFAQQANMVKHQMLHTGEKPFKCKSCDKAFSQNANLKKHEMVHLGIRPHTCPLCTKSYSQYSNL 428

  Fly   324 TTHYRSNAHRRNMQKAD 340
            ..|..|  |::...|.:
Mosquito   429 KKHLLS--HQKQAIKQE 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	17/53 (32%)
		C2H2 Zn finger	226..246	CDD:275368	5/19 (26%)
		zf-H2C2_2	238..262	CDD:290200	8/23 (35%)
		C2H2 Zn finger	254..274	CDD:275368	5/19 (26%)
		zf-H2C2_2	269..291	CDD:290200	12/21 (57%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	10/23 (43%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
AgaP_AGAP005978	XP_556655.3	C2H2 Zn finger	51..71	CDD:275368
		C2H2 Zn finger	79..99	CDD:275368
		C2H2 Zn finger	107..127	CDD:275368
		COG5048	131..446	CDD:227381	49/147 (33%)
		C2H2 Zn finger	135..155	CDD:275368
		C2H2 Zn finger	163..183	CDD:275368
		C2H2 Zn finger	191..211	CDD:275368
		C2H2 Zn finger	219..239	CDD:275368
		C2H2 Zn finger	247..267	CDD:275368
		C2H2 Zn finger	275..295	CDD:275368
		C2H2 Zn finger	303..323	CDD:275368	4/19 (21%)
		C2H2 Zn finger	331..351	CDD:275368	5/19 (26%)
		C2H2 Zn finger	359..379	CDD:275368	5/19 (26%)
		zf-H2C2_2	371..396	CDD:290200	12/24 (50%)
		C2H2 Zn finger	387..407	CDD:275368	8/19 (42%)
		C2H2 Zn finger	415..435	CDD:275368	9/21 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910