DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC116407552

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_031748855.1	Gene:	LOC116407552 / 116407552	-ID:	-	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	344	Identity:	95/344 - (27%)
Similarity:	128/344 - (37%)	Gaps:	90/344 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGK------------RTNAERSL-------NIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRL 51
            |..|||            ||:.:..|       ..|.|.:..|: |.:..||....:||.
Frog   363 CSECGKCFSRKSYLDYHQRTHIKEKLFSCSECGKCFSKESNLTI-HYRTHTGEKPFSCSE----- 421

  Fly    52 CASCQTCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERL 116
            |..|         |.|:    .|..:|.:....      |.|.|.:|..:...|.:.:
Frog   422 CGKC---------FSEQ----SRLKIHYRTHTG------EKPFSCVECGKCFSDRSHL------- 460

  Fly   117 DDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPK 181
                                  ||:......|.....||.            .|..|:....:..
Frog   461 ----------------------KIHRRIHTGEKPFSCSEC------------GKCFLRKYHLHSH 491

  Fly   182 KRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKH 246
            :|.::|     .:||.|.|||.....:....:|.:.|.|.|.|.|..|...|...::||.|.|.|
Frog   492 ERTHKR-----EKTFSCSECGKCFSQQSRLKIHYRTHTGEKPFSCVECGKCFSDQSQLKIHHRTH 551

  Fly   247 TGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCD 311
            ||||||.|..|.:.||:.|....|.||||.|:||.|.||...|:....||.|..:|||||.|.|.
Frog   552 TGEKPFSCSECGKCFSEQSQLKIHHRTHTGEKPFSCSECGKCFSEQSRLKIHYRIHTGEKPFSCS 616

  Fly   312 LCDKLFSRYTHLTTHYRSN 330
            .|.|.||..:.|..|||::
Frog   617 ECGKCFSEQSQLKIHYRTH 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	20/89 (22%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	25/53 (47%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	12/21 (57%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
LOC116407552	XP_031748855.1	C2H2 Zn finger	27..47	CDD:275368
		C2H2 Zn finger	55..75	CDD:275368
		C2H2 Zn finger	83..103	CDD:275368
		C2H2 Zn finger	111..131	CDD:275368
		COG5048	135..548	CDD:227381	51/255 (20%)
		C2H2 Zn finger	139..159	CDD:275368
		C2H2 Zn finger	167..187	CDD:275368
		C2H2 Zn finger	195..215	CDD:275368
		C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368	5/19 (26%)
		COG5048	385..772	CDD:227381	89/322 (28%)
		C2H2 Zn finger	391..411	CDD:275368	4/20 (20%)
		C2H2 Zn finger	419..439	CDD:275368	8/37 (22%)
		C2H2 Zn finger	447..467	CDD:275368	4/48 (8%)
		C2H2 Zn finger	475..495	CDD:275368	5/31 (16%)
		C2H2 Zn finger	503..523	CDD:275368	5/19 (26%)
		C2H2 Zn finger	531..551	CDD:275368	7/19 (37%)
		C2H2 Zn finger	559..579	CDD:275368	7/19 (37%)
		C2H2 Zn finger	587..607	CDD:275368	7/19 (37%)
		C2H2 Zn finger	615..635	CDD:275368	9/19 (47%)
		C2H2 Zn finger	643..663	CDD:275368
		C2H2 Zn finger	671..691	CDD:275368
		C2H2 Zn finger	699..719	CDD:275368
		C2H2 Zn finger	727..747	CDD:275368
		C2H2 Zn finger	755..775	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8468
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000