DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC110439458

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021331156.1	Gene:	LOC110439458 / 110439458	-ID:	-	Length:	1672	Species:	Danio rerio

Alignment Length:	410	Identity:	110/410 - (26%)
Similarity:	148/410 - (36%)	Gaps:	134/410 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQ-------------- 56
            |..|||..|....||          :||::.||.....|:........|..
Zfish   551 CTQCGKSFNCSSHLN----------QHIRIHTGEKPFRCTQCGKSFNCSSHLNEHMMIHTGERPF 605

  Fly    57 TCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNE 121
            ||.|...||.:.....:...:|: .::.|  .|.|..||..:...|.|.:        |: ...|
Zfish   606 TCTQCGKSFSKSSSLYRHMKIHT-GEKPF--TCTECRKSFSQSSSLNLHM--------RI-HTGE 658

  Fly   122 GPIQ-----SSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPK 181
            .|..     :|..|...:....||:.           .|..:...|.     .|..::|...|..
Zfish   659 KPFTCTECGNSFSKSSSLYRHMKIHT-----------GEKPFTCTEC-----GKSFIQSSCLNVH 707

  Fly   182 KRRNRRNPRDSNRTFFCEECG------NHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELK 240
            .|.:     ...:.|.|.:||      :|:|.      |.|.|.||:|:.|..||..|.|.||||
Zfish   708 MRIH-----TGEKPFTCTQCGKSFSTSSHLKK------HMKIHTGVREYMCLECEKTFITAAELK 761

  Fly   241 RHIRKHTGEKPFKCRHCSRSFS------------------------------------------- 262
            ||.|.||||||:||..||:|||
Zfish   762 RHKRIHTGEKPYKCSQCSKSFSRSSHLNEHMKIHTREKPFTCTQCGKGFTLSSHLNRHKKIHTRE 826

  Fly   263 ------------DYSTRL-KHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCD 314
                        :||:.| :|.|.||.|:||.|.:|..:|:.|..|..||::|||||.|.|.||.
Zfish   827 KPFTCTQCGKTFNYSSCLNEHTRIHTGEKPFTCTQCGKSFSQSSHLNEHMMIHTGEKPFTCTLCG 891

  Fly   315 KLFSR----YTHLTTHYRSN 330
            |.|.|    .||:|.|...|
Zfish   892 KSFGRNFDLKTHMTIHTGEN 911

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	18/84 (21%)
		C2H2 Zn finger	198..218	CDD:275368	7/25 (28%)
		COG5048	222..>276	CDD:227381	32/109 (29%)
		C2H2 Zn finger	226..246	CDD:275368	12/19 (63%)
		zf-H2C2_2	238..262	CDD:290200	17/23 (74%)
		C2H2 Zn finger	254..274	CDD:275368	11/75 (15%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	14/23 (61%)
		C2H2 Zn finger	310..328	CDD:275368	10/21 (48%)
LOC110439458	XP_021331156.1	C2H2 Zn finger	49..68	CDD:275368
		C2H2 Zn finger	76..96	CDD:275368
		C2H2 Zn finger	104..124	CDD:275368
		C2H2 Zn finger	132..152	CDD:275368
		C2H2 Zn finger	160..180	CDD:275368
		C2H2 Zn finger	188..208	CDD:275368
		COG5048	212..590	CDD:227381	12/48 (25%)
		C2H2 Zn finger	216..236	CDD:275368
		C2H2 Zn finger	244..264	CDD:275368
		C2H2 Zn finger	272..292	CDD:275368
		C2H2 Zn finger	300..320	CDD:275368
		C2H2 Zn finger	328..348	CDD:275368
		C2H2 Zn finger	356..376	CDD:275368
		C2H2 Zn finger	384..404	CDD:275368
		COG5048	408..821	CDD:227381	76/318 (24%)
		C2H2 Zn finger	412..432	CDD:275368
		C2H2 Zn finger	440..460	CDD:275368
		C2H2 Zn finger	468..488	CDD:275368
		C2H2 Zn finger	496..516	CDD:275368
		C2H2 Zn finger	551..571	CDD:275368	9/29 (31%)
		C2H2 Zn finger	579..599	CDD:275368	2/19 (11%)
		C2H2 Zn finger	607..627	CDD:275368	4/19 (21%)
		C2H2 Zn finger	635..655	CDD:275368	7/28 (25%)
		C2H2 Zn finger	663..683	CDD:275368	3/19 (16%)
		C2H2 Zn finger	691..711	CDD:275368	5/24 (21%)
		C2H2 Zn finger	719..739	CDD:275368	7/25 (28%)
		C2H2 Zn finger	747..767	CDD:275368	12/19 (63%)
		C2H2 Zn finger	775..795	CDD:275368	6/19 (32%)
		C2H2 Zn finger	803..823	CDD:275368	0/19 (0%)
		C2H2 Zn finger	831..851	CDD:275368	5/19 (26%)
		C2H2 Zn finger	859..879	CDD:275368	7/19 (37%)
		C2H2 Zn finger	887..907	CDD:275368	9/19 (47%)
		C2H2 Zn finger	915..935	CDD:275368
		COG5048	939..1342	CDD:227381
		C2H2 Zn finger	943..963	CDD:275368
		C2H2 Zn finger	971..991	CDD:275368
		C2H2 Zn finger	999..1019	CDD:275368
		C2H2 Zn finger	1027..1047	CDD:275368
		C2H2 Zn finger	1055..1075	CDD:275368
		C2H2 Zn finger	1083..1103	CDD:275368
		C2H2 Zn finger	1111..1131	CDD:275368
		C2H2 Zn finger	1139..1159	CDD:275368
		C2H2 Zn finger	1167..1187	CDD:275368
		COG5048	1191..1626	CDD:227381
		C2H2 Zn finger	1195..1215	CDD:275368
		C2H2 Zn finger	1223..1243	CDD:275368
		C2H2 Zn finger	1251..1271	CDD:275368
		C2H2 Zn finger	1279..1299	CDD:275368
		C2H2 Zn finger	1307..1327	CDD:275368
		C2H2 Zn finger	1335..1355	CDD:275368
		C2H2 Zn finger	1363..1382	CDD:275368
		C2H2 Zn finger	1390..1410	CDD:275368
		C2H2 Zn finger	1418..1438	CDD:275368
		C2H2 Zn finger	1446..1466	CDD:275368
		C2H2 Zn finger	1475..1495	CDD:275368
		C2H2 Zn finger	1503..1523	CDD:275368
		C2H2 Zn finger	1531..1551	CDD:275368
		C2H2 Zn finger	1559..1579	CDD:275368
		C2H2 Zn finger	1587..1607	CDD:275368
		C2H2 Zn finger	1615..1635	CDD:275368
		C2H2 Zn finger	1643..1663	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910