DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ranshi and xlcgf26.1l

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_031749206.1	Gene:	xlcgf26.1l / 108645154	XenbaseID:	XB-GENE-22065104	Length:	1159	Species:	Xenopus tropicalis

Alignment Length:	479	Identity:	108/479 - (22%)
Similarity:	155/479 - (32%)	Gaps:	172/479 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCL 70
            ||.|||..:...||:...:.:||.  .|:|         :.|..:..:..|.|..:...:|..|:
Frog   559 CRECGKSFSVRNSLHKHMRVHQTM--DIEL---------AALVPKAGSGSQCCCGKPGIWRHLCI 612

  Fly    71 ------EVQREL-----------LHSQDDEDFLRICQESPKSVLEQ------------EELELDL 106
                  .|:|:|           :|.:.|.....:....|.|:|.:            ...:..|
Frog   613 LYRAAPLVERKLSAYTVNMDQGSVHLKIDRGTQSVITMEPPSLLRKPRKLKGKIGNKPRNSKYHL 677

  Fly   107 AEISIEVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDY-------------SEMDY 158
            :.|..::..|    .||   |..:||..:|:.|..|.:..:||.::.             ||.|.
Frog   678 SSIKSKMGSL----SGP---SSPEVEHNINQVKREEMDSGSEDGLNSLPREVKMETVELDSECDP 735

  Fly   159 LIYESDTEVD------------------------------------------------------- 168
            ...|.|.|.:
Frog   736 DTAEGDPEAEVLQIKVEEEDYDPSAVESEECAASDTEGCLHDKRSWARHYSLTVSGSSDSSGGLD 800

  Fly   169 ----------------AKQELKSDSENPK----------------------------KRRNRRNP 189
                            |....:||||..:                            ...|..||
Frog   801 KSMDFVGSRQPPDTGKANARCESDSETQESSCFVCNECGKYFLLQSEFLSHPCVSDTNMDNTGNP 865

  Fly   190 -----------RDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHI 243
                       ....:.|.|.|||..|..:.:...|.|.|||.|.|.|..|...|.....|..|:
Frog   866 LRSCCQLHLLAHSDGKPFTCTECGKGISTKSNLQSHQKIHRGAKPFVCTQCGKGFSRKYSLNNHV 930

  Fly   244 RKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAF 308
            |.|||:|||.|..|.:||.:.|....|.:.||.|:||:|..|...|:....|.||..:|||||.|
Frog   931 RFHTGDKPFVCTECGKSFPEKSKLHSHVKIHTGEKPFICPVCGKGFSEKCNLYNHQTIHTGEKPF 995

  Fly   309 RCDLCDKLFSRYTHLTTHYRSNAH 332
            .|..|.:.|||.:.|:.|  .|.|
Frog   996 MCPECGERFSRKSTLSIH--KNVH 1017

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	19/87 (22%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	9/21 (43%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
xlcgf26.1l	XP_031749206.1	C2H2 Zn finger	190..209	CDD:275368
		COG5048	219..>545	CDD:227381
		C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368
		C2H2 Zn finger	419..439	CDD:275368
		C2H2 Zn finger	447..467	CDD:275368
		C2H2 Zn finger	475..495	CDD:275368
		C2H2 Zn finger	503..523	CDD:275368
		C2H2 Zn finger	531..551	CDD:275368
		C2H2 Zn finger	559..579	CDD:275368	7/19 (37%)
		C2H2 Zn finger	835..877	CDD:275368	3/41 (7%)
		COG5048	<855..1071	CDD:227381	60/165 (36%)
		C2H2 Zn finger	885..905	CDD:275368	7/19 (37%)
		C2H2 Zn finger	913..933	CDD:275368	6/19 (32%)
		C2H2 Zn finger	941..961	CDD:275368	6/19 (32%)
		C2H2 Zn finger	969..989	CDD:275368	6/19 (32%)
		C2H2 Zn finger	997..1017	CDD:275368	8/21 (38%)
		C2H2 Zn finger	1025..1045	CDD:275368
		C2H2 Zn finger	1053..1073	CDD:275368
		C2H2 Zn finger	1081..1101	CDD:275368
		zf-C2H2	1107..1129	CDD:395048
		C2H2 Zn finger	1109..1129	CDD:275368
		C2H2 Zn finger	1137..1157	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910