DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC108182721

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021326715.1	Gene:	LOC108182721 / 108182721	-ID:	-	Length:	416	Species:	Danio rerio

Alignment Length:	330	Identity:	88/330 - (26%)
Similarity:	124/330 - (37%)	Gaps:	67/330 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 HIK------LLTGAVL----KNCSTLPNRLCASCQTCLQQAISFRER-----------CLEVQRE 75
            |:|      |.|..||    |||.|     |..|...|......:..           |.:..:.
Zfish    30 HVKIEDKTHLETDGVLKVRDKNCFT-----CTPCDKSLASKSKLKTHMRIHTGEKPFTCTQCGKS 89

  Fly    76 LLHSQDDEDFLRI--------CQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQ----SSG 128
            ..||......:||        |.:..||..:...|   ...:.|..      .|.|:.    ...
Zfish    90 FSHSSSLNQHMRIHTGEKPFTCTQCGKSFSKSSSL---YKHMKIHT------GEKPLTCTHCGKS 145

  Fly   129 FKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSN 193
            |.....||                   :...|:..:..:...|..||.|::....::.: .....
Zfish   146 FNHSSFLN-------------------LHMRIHTGEKPLTCPQCGKSFSKSSSLYKHMK-IHTGE 190

  Fly   194 RTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCS 258
            :.|.|.:||....|......|.:.|.|.|.|.|..|...|...:.||:|:..|||||||.|..|.
Zfish   191 KPFTCTQCGKSFYDSSYLKKHMRIHTGEKPFTCAQCGKSFNCSSHLKKHMMIHTGEKPFTCTQCG 255

  Fly   259 RSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHL 323
            :|||..|:..:|.|.||.|:||.|.:|..:|:.|..|..|:::|||||.|.|..|.|.|...::|
Zfish   256 KSFSKSSSLYRHMRIHTGEKPFTCTQCGKSFSHSSSLNQHIMIHTGEKPFTCPQCGKSFIHSSNL 320

  Fly   324 TTHYR 328
            ..|.|
Zfish   321 NLHMR 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	14/65 (22%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	24/53 (45%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
LOC108182721	XP_021326715.1	COG5048	53..415	CDD:227381	79/307 (26%)
		C2H2 Zn finger	55..75	CDD:275368	3/19 (16%)
		C2H2 Zn finger	83..103	CDD:275368	4/19 (21%)
		C2H2 Zn finger	111..131	CDD:275368	4/22 (18%)
		C2H2 Zn finger	139..159	CDD:275368	3/38 (8%)
		C2H2 Zn finger	167..187	CDD:275368	4/20 (20%)
		C2H2 Zn finger	195..215	CDD:275368	5/19 (26%)
		C2H2 Zn finger	223..243	CDD:275368	6/19 (32%)
		C2H2 Zn finger	251..271	CDD:275368	8/19 (42%)
		C2H2 Zn finger	279..299	CDD:275368	6/19 (32%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910