DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC105945434

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_017944994.2	Gene:	LOC105945434 / 105945434	-ID:	-	Length:	1056	Species:	Xenopus tropicalis

Alignment Length:	371	Identity:	94/371 - (25%)
Similarity:	137/371 - (36%)	Gaps:	65/371 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQT------------------TLEHIKLLTGAVLKNCSTLPNRLC 52
            |..|||...|...|.:.::|..|                  .:.|.:..||....:||.     |
Frog   605 CTECGKCFAASSELTVHQQRTHTGEKLSCSKCGKRFSRRSNLIRHHRTHTGEKPFSCSE-----C 664

  Fly    53 ASCQTCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLD 117
            ..|         |..|....:.:..|: .::.|  .|.|..||.....:|.:...::....:...
Frog   665 GKC---------FLNRSNLARHQSTHT-GEKPF--SCSECQKSFASSSKLTVHQRQVHTTEKPFS 717

  Fly   118 DLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYS----------EMDYLIYESDTEVDAKQE 172
            ....|...|..|         .....:..:..|..||          ..:..|::.......|..
Frog   718 CSECGKCFSDRF---------IFTRHQRTHTGDKPYSCSECGKCFATSSECTIHQRRIHTGEKPF 773

  Fly   173 LKSD-----SENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDR 232
            ..||     :.:.|...::|......:.|.|.|||....||.:|..|.:.|.|||.|.|..|...
Frog   774 SCSDCGKCFASSSKLTVHQRQVHTMEKPFSCSECGKCFSDRSNFARHQRTHTGVKPFSCSECGKC 838

  Fly   233 FCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKN 297
            |.....|..|::.|||||||.|..|.:.||.:::...|.:|||..:||.|.||...|.....|..
Frog   839 FSAHTTLACHLKTHTGEKPFSCSECGKCFSAHTSLACHLKTHTGAKPFSCSECGKCFLNRSNLVR 903

  Fly   298 HMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKADTIF 343
            |..:|||||.|.|..|:|.|:..:.|      |.|||.:..::..|
Frog   904 HQSIHTGEKPFSCSECEKCFASSSEL------NVHRRQVHTSEKPF 943

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	17/88 (19%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	5/19 (26%)
		zf-H2C2_2	238..262	CDD:290200	11/23 (48%)
		C2H2 Zn finger	254..274	CDD:275368	5/19 (26%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	5/17 (29%)
LOC105945434	XP_017944994.2	KRAB_A-box	88..>117	CDD:413388
		C2H2 Zn finger	242..262	CDD:275368
		C2H2 Zn finger	271..290	CDD:275368
		COG5048	294..700	CDD:227381	23/111 (21%)
		C2H2 Zn finger	298..318	CDD:275368
		C2H2 Zn finger	326..346	CDD:275368
		C2H2 Zn finger	354..374	CDD:275368
		C2H2 Zn finger	382..402	CDD:275368
		C2H2 Zn finger	410..430	CDD:275368
		C2H2 Zn finger	438..458	CDD:275368
		C2H2 Zn finger	466..486	CDD:275368
		C2H2 Zn finger	494..514	CDD:275368
		C2H2 Zn finger	522..542	CDD:275368
		C2H2 Zn finger	550..570	CDD:275368
		COG5048	575..990	CDD:227381	94/371 (25%)
		C2H2 Zn finger	578..597	CDD:275368
		C2H2 Zn finger	605..626	CDD:275368	7/20 (35%)
		C2H2 Zn finger	633..653	CDD:275368	1/19 (5%)
		C2H2 Zn finger	661..681	CDD:275368	6/33 (18%)
		C2H2 Zn finger	689..707	CDD:275368	5/17 (29%)
		C2H2 Zn finger	718..738	CDD:275368	3/28 (11%)
		C2H2 Zn finger	746..767	CDD:275368	1/20 (5%)
		C2H2 Zn finger	775..793	CDD:275368	3/17 (18%)
		C2H2 Zn finger	804..824	CDD:275368	8/19 (42%)
		C2H2 Zn finger	832..852	CDD:275368	5/19 (26%)
		C2H2 Zn finger	860..880	CDD:275368	5/19 (26%)
		C2H2 Zn finger	888..908	CDD:275368	6/19 (32%)
		C2H2 Zn finger	916..934	CDD:275368	7/23 (30%)
		C2H2 Zn finger	945..965	CDD:275368
		C2H2 Zn finger	973..994	CDD:275368
		C2H2 Zn finger	1002..1023	CDD:275368
		C2H2 Zn finger	1031..1051	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8468
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000