DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC103910773

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021331338.1	Gene:	LOC103910773 / 103910773	-ID:	-	Length:	696	Species:	Danio rerio

Alignment Length:	399	Identity:	102/399 - (25%)
Similarity:	149/399 - (37%)	Gaps:	92/399 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTG---------AVLKNCSTLPNR----------- 50
            |..|||..|...|||:          |:::.||         ....:||:..||
Zfish   264 CTRCGKSFNCSSSLNL----------HMRIHTGEKPFTCTRCGKSFSCSSSLNRHMRIHTGEKPF 318

  Fly    51 LCASCQTCLQQAISFRER-----------CLEVQRELLHSQDDEDFLRI--------CQESPKSV 96
            .|..|:....|:....|.           |.:.::....|.:..:.::|        |.:..||.
Zfish   319 TCTQCEKSFSQSSHLNEHMRIHTGKKPFTCAQCEKSFSQSSNLNNHMKIHTGEKPFTCTQCGKSF 383

  Fly    97 LEQEELELDL-----------AEISIEVERLDDLN--------EGPIQ----SSGFKVEDILN-E 137
            ..|..|::.:           .:......:|.:||        |.|..    ...|.:::.|. .
Zfish   384 GIQSSLKIHMRIHTGEKPFTCTQCGRSYHQLSNLNNHMKIHTGEKPYTCTQCGKSFGIQNTLKIH 448

  Fly   138 SKINEDEP-----------NNEDDIDYSEMDYLIYESDTEVDAKQELK--SDSENPKKRRNRRNP 189
            .:|:..|.           |....::   :..:|:..:......|..|  |.|.|..|.....:
Zfish   449 MRIHTGEKPFTCTQCGRSFNQSSSLN---LHMMIHTGEKPFTCTQCGKRFSQSSNFNKHMKIHS- 509

  Fly   190 RDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKC 254
              ..:.|.|.:||........|.||.:.|.|.|.|.|..|...|...:.|..|:|.|||||||.|
Zfish   510 --GEKPFTCHQCGKSFSRPSHFNLHMRIHTGEKPFICTQCGKSFSQSSNLNSHMRIHTGEKPFTC 572

  Fly   255 RHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSR 319
            ..|.:|||..|:...|.|.||.|:||.|.:|..:|:....|..||.:|||||.|.|..|.|.||:
Zfish   573 TQCGKSFSQLSSLNLHMRLHTGEKPFTCTQCGKSFSQLSSLNLHMRIHTGEKPFTCTQCGKSFSQ 637

  Fly   320 YTHLTTHYR 328
            ..||..|.|
Zfish   638 SAHLNKHKR 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	20/101 (20%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	24/53 (45%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
LOC103910773	XP_021331338.1	C2H2 Zn finger	68..88	CDD:275368
		zf-H2C2_2	81..105	CDD:316026
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		zf-H2C2_2	137..161	CDD:316026
		C2H2 Zn finger	152..172	CDD:275368
		zf-H2C2_2	164..189	CDD:316026
		C2H2 Zn finger	180..200	CDD:275368
		COG5048	203..646	CDD:227381	101/397 (25%)
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368	9/29 (31%)
		C2H2 Zn finger	292..312	CDD:275368	4/19 (21%)
		C2H2 Zn finger	320..340	CDD:275368	4/19 (21%)
		C2H2 Zn finger	348..368	CDD:275368	2/19 (11%)
		C2H2 Zn finger	376..396	CDD:275368	5/19 (26%)
		C2H2 Zn finger	404..424	CDD:275368	3/19 (16%)
		C2H2 Zn finger	432..452	CDD:275368	2/19 (11%)
		C2H2 Zn finger	460..480	CDD:275368	1/22 (5%)
		C2H2 Zn finger	488..508	CDD:275368	6/19 (32%)
		C2H2 Zn finger	516..536	CDD:275368	6/19 (32%)
		C2H2 Zn finger	544..564	CDD:275368	6/19 (32%)
		C2H2 Zn finger	572..592	CDD:275368	8/19 (42%)
		C2H2 Zn finger	600..620	CDD:275368	6/19 (32%)
		C2H2 Zn finger	628..648	CDD:275368	9/19 (47%)
		C2H2 Zn finger	656..681	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910