DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ranshi and si:ch211-229l10.11

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021331165.1	Gene:	si:ch211-229l10.11 / 103910550	ZFINID:	ZDB-GENE-110913-131	Length:	850	Species:	Danio rerio

Alignment Length:	324	Identity:	82/324 - (25%)
Similarity:	125/324 - (38%)	Gaps:	82/324 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCL 70
            |:.|||..:...:|.:          |:::.||....:||        .|....:|.::.:
Zfish    68 CQHCGKSFSKTGNLAV----------HMRIHTGEKPYSCS--------QCGKSFKQNVTLK---- 110

  Fly    71 EVQRELLHSQ-DDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDI 134
                  :|.: .:|:.:..|.:..||:.::..|::::.
Zfish   111 ------IHMRTHNEERIFTCTQCGKSISQKHYLDINMR--------------------------- 142

  Fly   135 LNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCE 199
                            |...|..|...|.......|..||          :.|......:.|.|.
Zfish   143 ----------------IHTGEKPYTCTECGKSFPYKGSLK----------HHRISHTGEKPFTCT 181

  Fly   200 ECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDY 264
            :||.:.........|.:.|.|.|.|.|..|...|...|.|.:|:|.|||||||.|..|.:|||:.
Zfish   182 QCGKNFNQSSHLNQHMRIHTGEKPFTCTQCGKSFSYSANLNQHMRIHTGEKPFTCTQCGKSFSNS 246

  Fly   265 STRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYR 328
            :...:|.|.||.|:||.|.:|..:|:.|..|..||.:|||||.|.|..|.|.||:..:|..|.|
Zfish   247 ANLNQHMRIHTGEKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCTQCGKSFSQSPYLNQHMR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	12/70 (17%)
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	24/53 (45%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
si:ch211-229l10.11	XP_021331165.1	C2H2 Zn finger	12..32	CDD:275368
		zf-H2C2_2	25..49	CDD:316026
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368	6/29 (21%)
		zf-H2C2_2	80..105	CDD:316026	7/42 (17%)
		SFP1	<90..169	CDD:227516	18/149 (12%)
		C2H2 Zn finger	96..116	CDD:275368	5/37 (14%)
		C2H2 Zn finger	124..144	CDD:275368	4/62 (6%)
		C2H2 Zn finger	152..172	CDD:275368	5/29 (17%)
		COG5048	176..580	CDD:227381	56/135 (41%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		COG5048	400..841	CDD:227381
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	573..593	CDD:275368
		C2H2 Zn finger	601..621	CDD:275368
		C2H2 Zn finger	629..649	CDD:275368
		C2H2 Zn finger	657..677	CDD:275368
		C2H2 Zn finger	685..705	CDD:275368
		C2H2 Zn finger	713..733	CDD:275368
		C2H2 Zn finger	741..761	CDD:275368
		C2H2 Zn finger	769..789	CDD:275368
		C2H2 Zn finger	797..817	CDD:275368
		C2H2 Zn finger	825..845	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910