DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and znf1178

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021325086.1	Gene:	znf1178 / 103909503	ZFINID:	ZDB-GENE-050208-466	Length:	322	Species:	Danio rerio

Alignment Length:	326	Identity:	83/326 - (25%)
Similarity:	124/326 - (38%)	Gaps:	80/326 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GKVCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRE 67
            |.:|..|||..:.:.:|.:          |:::.||.....||...  :...|...|:
Zfish    61 GFICTQCGKSYSRKCALKL----------HMRIHTGEKPFKCSHCD--MSFFCSGYLK------- 106

  Fly    68 RCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVE 132
                 ..|:.|: .:..|  :|.:..||...:..|:|.:        |: ...|.|.:.|
Zfish   107 -----THEMTHT-GERPF--VCAQCGKSYSHKNNLKLHM--------RI-HTGEKPFKCS----- 149

  Fly   133 DILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFF 197
                                :.|..:                   .|....::.|......:.|.
Zfish   150 --------------------HCERRF-------------------SNAGHLKHHRMIHTGEKPFT 175

  Fly   198 CEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFS 262
            |.:||.....:.....|.:.|.||.:..|..|:..|.....|::|...||||||:.|.||.:|||
Zfish   176 CAQCGKSFTRQSCLAQHQQIHTGVSKHVCLMCQKTFIRAGNLRQHQMTHTGEKPYTCSHCDKSFS 240

  Fly   263 DYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHY 327
            .:.....|:||||.|:||.|.:|..:||.|..|..|||:|||||...||.|.|.|.|...|..|.
Zfish   241 QFKVLKIHQRTHTGEKPFTCTQCGKSFTQSSHLNRHMLIHTGEKTHICDQCSKTFLRPCELKRHL 305

  Fly   328 R 328
            :
Zfish   306 K 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	13/71 (18%)
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	5/19 (26%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	9/19 (47%)
		zf-H2C2_2	295..319	CDD:290200	14/23 (61%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
znf1178	XP_021325086.1	C2H2 Zn finger	64..84	CDD:275368	6/29 (21%)
		COG5048	<88..276	CDD:227381	58/257 (23%)
		C2H2 Zn finger	92..112	CDD:275368	5/33 (15%)
		C2H2 Zn finger	120..140	CDD:275368	6/28 (21%)
		C2H2 Zn finger	148..168	CDD:275368	4/63 (6%)
		C2H2 Zn finger	176..196	CDD:275368	4/19 (21%)
		C2H2 Zn finger	204..224	CDD:275368	5/19 (26%)
		C2H2 Zn finger	232..252	CDD:275368	8/19 (42%)
		C2H2 Zn finger	260..280	CDD:275368	9/19 (47%)
		C2H2 Zn finger	288..308	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910