DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ranshi and Zscan22

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_038956724.1	Gene:	Zscan22 / 102553002	RGDID:	7606541	Length:	495	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	94/315 - (29%)
Similarity:	136/315 - (43%)	Gaps:	41/315 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCLEVQRELLHSQDDEDFLR 87
            ::.|...||..::.|..::.:.|  |....|  |||..      |...|.|.|||.:      |.
  Rat   147 KQSNTDELEPPEMATETIMGSVS--PESTLA--QTCKP------ENSSESQPELLGA------LW 195

  Fly    88 ICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDILNESKI-NEDEPNNEDDI 151
            :     ||..::.:|:..|.      .|:|..|:.|...|.....|.....|. :||:.::|:
  Rat   196 V-----KSTAQEVDLKKALE------PRMDAPNDQPDHESDASGNDCSMLPKFPSEDKTSSEE-- 247

  Fly   152 DYSEMDYLIYESDTEVDAKQELKS--DSE------NPKKRRNRRNPRDSNRTFFCEECGNHIKDR 208
               :...|:......:|...|.||  |||      |...:...:........:.|.|||......
  Rat   248 ---KCGPLLDNETVPLDTCSEKKSSKDSECMRTLQNTSAQETHQKNHSQKTPYTCIECGKVFSRS 309

  Fly   209 ISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERT 273
            ...:.|...|.|.|...|:.|...|...|.|.:|.|.||||||:||..|.::||..:...:|:|.
  Rat   310 THLVQHQVVHTGAKPHACKECGKAFSRVAHLTQHQRIHTGEKPYKCEECGKTFSRSTHLTQHQRV 374

  Fly   274 HTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYR 328
            ||.|||:.|..|..||:.|..|..|..:|||||.:||::|.|.||..:.|..|.|
  Rat   375 HTGERPYECDTCGKAFSQSTHLTQHQRIHTGEKPYRCEVCGKAFSDCSALVRHLR 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	14/53 (26%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	22/53 (42%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
Zscan22	XP_038956724.1	SCAN	44..128	CDD:396558
		COG5048	<272..478	CDD:227381	57/158 (36%)
		C2H2 Zn finger	272..291	CDD:275368	3/18 (17%)
		C2H2 Zn finger	299..319	CDD:275368	5/19 (26%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		C2H2 Zn finger	355..375	CDD:275368	6/19 (32%)
		C2H2 Zn finger	383..403	CDD:275368	7/19 (37%)
		C2H2 Zn finger	411..431	CDD:275368	8/19 (42%)
		C2H2 Zn finger	439..459	CDD:275368
		C2H2 Zn finger	467..487	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910