DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC102551340

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_038955362.1	Gene:	LOC102551340 / 102551340	RGDID:	7697243	Length:	948	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	94/384 - (24%)
Similarity:	143/384 - (37%)	Gaps:	106/384 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCST------LPNRL------------- 51
            |..|||..|....|:          :|..:.||..|..|..      .|:||
  Rat   416 CEVCGKAFNDSLVLS----------KHRAIHTGEKLYKCDVCGKAFYYPSRLNNHRKIHSGEKPY 470

  Fly    52 -CASC--QTCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEV 113
             |..|  ..|...::|..:|        :|:.:.....:.|.::.:|:            .|:..
  Rat   471 QCEECGKAFCFPSSLSKHKR--------IHTGEKPYKCKECDKAFRSL------------SSLSK 515

  Fly   114 ERLDDLNEGP----IQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELK 174
            .|.....|.|    :....|....:|::.||...|          |..|           |.|:.
  Rat   516 HRRIHTGEKPYKCEVCGKAFHYPSLLSKHKITHTE----------EKPY-----------KCEVC 559

  Fly   175 SDSEN-PKKRRNRRNPRDSNRTFFCEECG-------------------NHIKDRIS---FIL--- 213
            ....: |.|..:.:........:.||.||                   ||...::|   ||.
  Rat   560 GQGFHVPSKLSHHKIIHTGESPYKCEVCGKAFCIPLLLSKHKISHTGENHSNSQLSKKAFIYPSR 624

  Fly   214 ---HCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHT 275
               |.|.|:.||.:.||.|...|..|:.|..|...||||||:||..|.::|...|...||:|.||
  Rat   625 LSKHKKIHKRVKPYKCEVCGKAFRFPSLLLIHKGIHTGEKPYKCEECGKAFYYPSLLSKHKRVHT 689

  Fly   276 NERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRR 334
            .|:|:.|:.|...|..|..|..|.::|||||.::|::|:|.|...:.|:.|.|.:..::
  Rat   690 GEKPYQCEVCGKGFHVSSSLSKHRIIHTGEKPYKCEVCEKAFRFSSSLSKHKRIHTGKK 748

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	19/92 (21%)
		C2H2 Zn finger	198..218	CDD:275368	11/47 (23%)
		COG5048	222..>276	CDD:227381	23/53 (43%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	11/23 (48%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
LOC102551340	XP_038955362.1	KRAB	2..60	CDD:214630
		C2H2 Zn finger	108..128	CDD:275368
		SFP1	<131..199	CDD:227516
		C2H2 Zn finger	136..156	CDD:275368
		C2H2 Zn finger	164..184	CDD:275368
		C2H2 Zn finger	192..212	CDD:275368
		COG5048	216..657	CDD:227381	57/291 (20%)
		C2H2 Zn finger	220..240	CDD:275368
		C2H2 Zn finger	248..268	CDD:275368
		C2H2 Zn finger	276..296	CDD:275368
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	332..352	CDD:275368
		C2H2 Zn finger	360..380	CDD:275368
		C2H2 Zn finger	389..408	CDD:275370
		C2H2 Zn finger	416..436	CDD:275368	7/29 (24%)
		C2H2 Zn finger	444..464	CDD:275368	4/19 (21%)
		COG5048	468..910	CDD:227381	80/322 (25%)
		C2H2 Zn finger	472..492	CDD:275368	5/27 (19%)
		C2H2 Zn finger	500..520	CDD:275368	4/31 (13%)
		C2H2 Zn finger	528..548	CDD:275368	4/19 (21%)
		C2H2 Zn finger	556..576	CDD:275368	3/19 (16%)
		C2H2 Zn finger	584..604	CDD:275368	4/19 (21%)
		C2H2 Zn finger	640..660	CDD:275368	7/19 (37%)
		C2H2 Zn finger	668..688	CDD:275368	7/19 (37%)
		C2H2 Zn finger	696..716	CDD:275368	6/19 (32%)
		C2H2 Zn finger	724..744	CDD:275368	7/19 (37%)
		C2H2 Zn finger	752..772	CDD:275368
		C2H2 Zn finger	780..800	CDD:275368
		C2H2 Zn finger	808..828	CDD:275368
		C2H2 Zn finger	836..856	CDD:275368
		C2H2 Zn finger	864..884	CDD:275368
		C2H2 Zn finger	892..912	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910