Protein Alignment ranshi and ZNF443

DIOPT Version :9

• Sequence 1: NP_649824.1
• Gene: ranshi / 41041
• FlyBaseID: FBgn0037620
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_005806.3
• Gene: ZNF443 / 10224
• HGNCID: 20878
• Length: 671
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 81/277 - (29%)
• Similarity: 127/277 - (45%)
• Gaps: 51/277 - (18%)

  Fly    68 RCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVE 132
            ||..::| .:.|:|...    |.|:...:.:....:..|..:            ||.:|| .:.|
Human    64 RCRMLER-FVESKDGTQ----CGETSSQIQDSIVTKNTLPGV------------GPCESS-MRGE 110

  Fly   133 DILNESKIN-------EDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDS-----ENPKKRRN 185
            .::..|.:|       ..:|:     :|.|..   .:.||.   ||..|:.|     :..::...
Human   111 KVMGHSSLNCYIRVGAGHKPH-----EYHECG---EKPDTH---KQRGKAFSYHNSFQTHERLHT 164

  Fly   186 RRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEK 250
            .:.|.|      |:|||.......:...|....||...:.|:.|...|..|:.|..|.|.|||||
Human   165 GKKPYD------CKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTHTGEK 223

  Fly   251 PFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFT--TSYILKNHMLVHTGEKAFRCDLC 313
            |::|:.||::||.||:.|:||||||.|:|:.||:|:.||.  :||:  .|...|||||.::|..|
Human   224 PYECKQCSKAFSFYSSYLRHERTHTGEKPYECKQCSKAFPFYSSYL--RHERTHTGEKPYKCKQC 286

  Fly   314 DKLFSRYTHLTTHYRSN 330
            .|.|...:....|.|::
Human   287 SKAFPDSSSCLIHERTH 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	3/8 (38%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	26/53 (49%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	11/19 (58%)
		zf-H2C2_2	269..291	CDD:290200	13/23 (57%)
		C2H2 Zn finger	282..302	CDD:275368	8/21 (38%)
		zf-H2C2_2	295..319	CDD:290200	10/23 (43%)
		C2H2 Zn finger	310..328	CDD:275368	5/17 (29%)
ZNF443	NP_005806.3	KRAB	3..43	CDD:307490
		C2H2 Zn finger	133..163	CDD:275368	8/35 (23%)
		C2H2 Zn finger	171..191	CDD:275368	5/19 (26%)
		COG5048	196..579	CDD:227381	48/110 (44%)
		C2H2 Zn finger	199..219	CDD:275368	7/19 (37%)
		C2H2 Zn finger	227..247	CDD:275368	11/19 (58%)
		C2H2 Zn finger	255..275	CDD:275368	8/21 (38%)
		C2H2 Zn finger	283..303	CDD:275368	6/19 (32%)
		C2H2 Zn finger	311..331	CDD:275368
		C2H2 Zn finger	339..359	CDD:275368
		C2H2 Zn finger	367..387	CDD:275368
		C2H2 Zn finger	395..415	CDD:275368
		C2H2 Zn finger	423..443	CDD:275368
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	506..526	CDD:275368
		C2H2 Zn finger	534..554	CDD:275368
		C2H2 Zn finger	562..582	CDD:275368
		C2H2 Zn finger	590..610	CDD:275368
		C2H2 Zn finger	618..638	CDD:275368
		C2H2 Zn finger	651..671	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	0.118	Domainoid score	I11437
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000