DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and znf1168

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021325085.1	Gene:	znf1168 / 101883958	ZFINID:	ZDB-GENE-050208-703	Length:	329	Species:	Danio rerio

Alignment Length:	337	Identity:	96/337 - (28%)
Similarity:	139/337 - (41%)	Gaps:	74/337 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCLEVQRELLHSQD---DEDFLRICQESPKSVL 97
            :|.|:.::.|...:.|.::       |||.|:|     :.||...:   |.:..||.||..:
Zfish     1 MTSALTRSFSVESSELSSA-------AISERQR-----QSLLKDSEKMSDPEPCRIKQEETE--- 50

  Fly    98 EQEELELDLAEISIEVERLDDLNEGPIQSS----------------------------GFKVEDI 134
            |:.::.::..|:|.:.|:....:|...||.                            .||:..:
Zfish    51 EKIDVMVNSEELSKDEEKHHVRSETQTQSKTVRSFSMKRTAVKCFTCTLCGKGFSYNRPFKLHMM 115

  Fly   135 LNESKINEDEPNNEDDID--YSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRN----PRD-- 191
            ::..    :.|......|  :|:..:|         ...|:....|.|.......|    |.|
Zfish   116 IHTG----ERPYKCSHCDKRFSQFGHL---------KSHEMIHTGEKPYTCDQCSNTFLRPSDLK 167

  Fly   192 -------SNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGE 249
                   :.:.:.|.|||..........||...|.||:||.|..||..|.|...||:|...||||
Zfish   168 IHLRVHTNEKPYSCPECGKRFAQHAHLKLHQHVHTGVREFVCFECEKTFITAGHLKQHQMIHTGE 232

  Fly   250 KPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCD 314
            ||:.|.|||::||.......|||.||.|:||.|..|..:|..|..|.:|||.|||||..:||.|.
Zfish   233 KPYTCSHCSKTFSHIGHMNAHERVHTGEKPFACTHCGKSFRVSSSLNSHMLTHTGEKTHKCDQCG 297

  Fly   315 KLFSRYTHLTTH 326
            |.|.|.:||..|
Zfish   298 KSFLRRSHLNRH 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	9/40 (23%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	26/53 (49%)
		C2H2 Zn finger	226..246	CDD:275368	8/19 (42%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	14/23 (61%)
		C2H2 Zn finger	310..328	CDD:275368	9/17 (53%)
znf1168	XP_021325085.1	C2H2 Zn finger	97..117	CDD:275368	2/19 (11%)
		SFP1	<114..201	CDD:227516	16/99 (16%)
		C2H2 Zn finger	125..145	CDD:275368	4/28 (14%)
		COG5048	<149..309	CDD:227381	64/159 (40%)
		C2H2 Zn finger	153..173	CDD:275368	3/19 (16%)
		C2H2 Zn finger	181..201	CDD:275368	6/19 (32%)
		C2H2 Zn finger	209..229	CDD:275368	8/19 (42%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	265..285	CDD:275368	8/19 (42%)
		C2H2 Zn finger	293..313	CDD:275368	9/17 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910