DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC100495401

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_002931723.3	Gene:	LOC100495401 / 100495401	-ID:	-	Length:	1375	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	94/377 - (24%)
Similarity:	144/377 - (38%)	Gaps:	68/377 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EGKVCRTCGKR-------TNAERSLNIFEKRNQTTLEH---IKLLTGAVLKNCSTLPNRLCASCQ 56
            :|....:|.|:       .|:......::|.|...:.|   .|:....:...|:....|.....:
Frog  1021 KGSSLYSCIKKGIKNMYSQNSNTVNRAYKKHNINNMLHKKYFKIKATWISHECNKCGKRFIGKIK 1085

  Fly    57 TCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNE 121
            |..::|:..|:.|:|.|..:.:..     .|:|..|..|.|...|   |......:........:
Frog  1086 TAKEKAVQNRKNCVESQLGMKNKT-----CRLCVNSINSTLTGNE---DSTSNVRQTHTCSKCGK 1142

  Fly   122 GPIQSSGFKVED-----------------------ILNESKINEDEPNNEDDIDYSEMDYLIYES 163
            ...|.|.|.:.:                       :|...||::|..      .|..||......
Frog  1143 MFAQHSVFLLHERSHKEEKLHVCYACGKRFVQNQLLLRHEKIHKDRK------PYQCMDCGRTFH 1201

  Fly   164 DTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEF 228
            ..|:....:.....|.|               |.|.|||....|..:..:|.:.|.|.|.|.|..
Frog  1202 GREMFVMHQRSHKEEKP---------------FPCAECGKRFADNATLTVHTRIHTGEKPFRCSA 1251

  Fly   229 CEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSY 293
            |...|...:.|..|.|.||||||:.|.:|.|.|||.|:...|.||||.|:||.|..|..:|:.|.
Frog  1252 CGKCFSQHSTLVSHQRIHTGEKPYSCHYCRRRFSDRSSYATHVRTHTGEKPFNCSGCGKSFSQSS 1316

  Fly   294 ILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYR------SNAHRRNMQKA 339
            .|:.|..:|||:|.:.|.:|.|.|:..|.|.:|.:      :|....::|:|
Frog  1317 NLRRHERIHTGQKPYACSVCGKTFNDNTKLKSHQKTHNKEETNVKLNHLQEA 1368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	15/81 (19%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	25/53 (47%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	10/23 (43%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
LOC100495401	XP_002931723.3	KRAB	4..60	CDD:214630
		COG5048	950..1358	CDD:227381	91/365 (25%)
		C2H2 Zn finger	1137..1157	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1165..1185	CDD:275368	2/19 (11%)
		C2H2 Zn finger	1193..1213	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1221..1241	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1249..1269	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1277..1297	CDD:275368	9/19 (47%)
		C2H2 Zn finger	1305..1325	CDD:275368	6/19 (32%)
		zf-H2C2_2	1317..1341	CDD:404364	9/23 (39%)
		C2H2 Zn finger	1333..1353	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910