DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and znf397

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_002937466.2	Gene:	znf397 / 100490776	XenbaseID:	XB-GENE-6045024	Length:	407	Species:	Xenopus tropicalis

Alignment Length:	362	Identity:	94/362 - (25%)
Similarity:	131/362 - (36%)	Gaps:	111/362 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GKVCRTCGKRTNAERSLN-----------------IFEKRNQTTLEHIKLLTGAVLKNCSTLPNR 50
            |:.|.|.|.:|...|:|.                 |...|..:|.||.|             |..
Frog   122 GQSCLTEGHKTPKSRNLEQRPGPPEDERPSERRAIIGTDRVASTAEHDK-------------PQS 173

  Fly    51 L------------CASCQTCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELE 103
            :            |..|..|      |||....::.:..||:....|    .|..:|:|......
Frog   174 VGQQRIRRARKYWCGECGDC------FREHSHFLEHQASHSKQKGTF----TEHRQSLLSSRHQG 228

  Fly   104 LDLAEISIEVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVD 168
            |..|                                        .|...|.|         ..||
Frog   229 LQTA----------------------------------------ADSSTYPE---------CSVD 244

  Fly   169 AKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRF 233
            .       :|.||...:||||.:: :::.|::||.:.....|.|:|.:.|.|.:...|:.|...|
Frog   245 R-------TEGPKPATHRRNPVEA-KSYTCKDCGKNFTQNASLIVHQRTHTGERPHNCKVCGKSF 301

  Fly   234 CTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNH 298
            .:.:.|..|.|.||||:|:.|..|.:.|...|..:.|:|.||.|:|::|.||...|..|..|..|
Frog   302 ISGSYLVMHQRVHTGERPYACNECGKRFISSSNLIIHQRVHTGEKPYLCTECGKCFGHSSHLVRH 366

  Fly   299 MLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRN 335
            ..|||||:.|.|..|.|.|||.:||..|  ...|.||
Frog   367 QKVHTGERPFTCAECGKAFSRSSHLVRH--QIIHMRN 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	19/100 (19%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	18/53 (34%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	10/23 (43%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	9/17 (53%)
znf397	XP_002937466.2	COG5048	<197..398	CDD:227381	71/263 (27%)
		C2H2 Zn finger	266..286	CDD:275368	6/19 (32%)
		C2H2 Zn finger	294..314	CDD:275368	6/19 (32%)
		C2H2 Zn finger	322..342	CDD:275368	6/19 (32%)
		C2H2 Zn finger	350..370	CDD:275368	7/19 (37%)
		C2H2 Zn finger	378..398	CDD:275368	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910