DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC100489584

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_002937462.1	Gene:	LOC100489584 / 100489584	-ID:	-	Length:	400	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	79/288 - (27%)
Similarity:	119/288 - (41%)	Gaps:	76/288 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 AEISIEVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDY-SEMDYLIYESD------ 164
            :|:|.:.|..::.:...:|.:.            .|:.|:::..||| |..|:::.|.:
Frog     3 SEVSPKTENGEEPSSNSLQDTH------------EEESPDSDLGIDYPSGRDFILTEENNAPRYS 55

  Fly   165 -------------------TEVDAKQEL--KSDSE--NPKKR----------------------- 183
                               |:|.|:...  .:|.|  |||:|
Frog    56 LRRLKCCKSGKPRQSTGKSTKVSAQTSRPDHADEEVYNPKERIRDQQRDGHNQKTNTALKQKGQK 120

  Fly   184 RNR-----------RNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPA 237
            ||:           ..|....:|:.|.|||.........|:|.:.|.|.:.|.|..|...|...:
Frog   121 RNKDAAEISKLAIQYTPYKVQKTYICTECGRSCISSSHLIIHQRSHTGERPFSCTDCGKSFARKS 185

  Fly   238 ELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVH 302
            .|..|.|.|:||:|:.|.||.:||:..:|...|.|.||.|||:||.||..:||::..|..|...|
Frog   186 SLVIHERIHSGERPYTCTHCGKSFTSSATLSTHIRIHTGERPYVCWECGKSFTSNSSLFIHNRTH 250

  Fly   303 TGEKAFRCDLCDKLFSRYTHLTTHYRSN 330
            ||||.:.|..|.|.||..:.|..|.||:
Frog   251 TGEKPYICIECGKTFSCTSALVIHKRSH 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	20/53 (38%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	11/23 (48%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	12/21 (57%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
LOC100489584	XP_002937462.1	COG5048	<144..297	CDD:227381	54/135 (40%)
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		zf-H2C2_2	158..183	CDD:290200	8/24 (33%)
		C2H2 Zn finger	174..194	CDD:275368	6/19 (32%)
		zf-H2C2_2	186..211	CDD:290200	12/24 (50%)
		C2H2 Zn finger	202..222	CDD:275368	8/19 (42%)
		zf-H2C2_2	215..239	CDD:290200	12/23 (52%)
		C2H2 Zn finger	230..250	CDD:275368	7/19 (37%)
		zf-H2C2_2	242..267	CDD:290200	11/24 (46%)
		C2H2 Zn finger	258..278	CDD:275368	8/19 (42%)
		zf-H2C2_2	270..294	CDD:290200	4/9 (44%)
		C2H2 Zn finger	286..306	CDD:275368
		C2H2 Zn finger	314..334	CDD:275368
		zf-H2C2_2	326..350	CDD:290200
		C2H2 Zn finger	342..362	CDD:275368
		zf-H2C2_2	354..379	CDD:290200
		C2H2 Zn finger	370..390	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910