DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and si:ch211-162i8.2

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021331195.1	Gene:	si:ch211-162i8.2 / 100333435	ZFINID:	ZDB-GENE-110913-56	Length:	1662	Species:	Danio rerio

Alignment Length:	385	Identity:	104/385 - (27%)
Similarity:	144/385 - (37%)	Gaps:	88/385 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTG---------AVLKNCSTLPNR----------- 50
            |..|||..:...||||          |:::.||         ....|||:|.|:
Zfish   264 CTQCGKSFSQSSSLNI----------HMRIHTGEKPFTCTQCGKSFNCSSLLNKHMKIHTGEKPF 318

  Fly    51 LCASCQTCLQQAISFRERCLEVQRELLHSQDDEDFL-RICQES--PKSVLEQE------ELELDL 106
            .|..|......:.|       :.|.::....::.|: ..|.:|  ..|.|.|.      |.....
Zfish   319 ACTQCGRSFSHSSS-------LNRHMMRHTGEKPFMFNHCGKSFTQSSSLNQHTRIHTGEKPFTC 376

  Fly   107 AEISIEVERLDDLNEGPIQSSG---FKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVD 168
            .:......|...||:.....:|   |...| ..:|.....:.|....|...|..:...:.
Zfish   377 TDCGKRFSRSWHLNQHTRIHTGEKPFTCTD-CGKSFSRSWQLNQHMMIHTGEKPFTCIQC----- 435

  Fly   169 AKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRF 233
            .|...:|.|.|...|.:     ...:.|.|.:||.......:...|.|.|.|||.|.|..|...|
Zfish   436 GKSFCRSSSLNLHMRIH-----TGEKPFTCTQCGKSFSQSSNLNKHMKTHTGVKPFTCTQCGKSF 495

  Fly   234 CTPAELKRHIRKHTGEKPFKCRHCSRSFS---------------------------DYSTRLK-H 270
            ...::||:|:..|||||||.|..|.:|||                           ..|:.|. |
Zfish   496 SQSSDLKQHMMIHTGEKPFTCTQCGKSFSRSSHLNEHTMIHIREKPFTCTQCGKRFSLSSSLNLH 560

  Fly   271 ERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSN 330
            .|.||.|:||.|.:|..:|:.|..||.||.:|||||.|||..|.|.||:.:||..|..|:
Zfish   561 TRIHTGEKPFTCSQCRKSFSQSSNLKKHMRIHTGEKPFRCTQCGKSFSQSSHLNKHMMSH 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	20/90 (22%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	25/81 (31%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	9/47 (19%)
		zf-H2C2_2	269..291	CDD:290200	10/22 (45%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	15/23 (65%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
si:ch211-162i8.2	XP_021331195.1	COG5048	62..471	CDD:227381	46/234 (20%)
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368	9/29 (31%)
		C2H2 Zn finger	292..312	CDD:275368	5/19 (26%)
		C2H2 Zn finger	320..340	CDD:275368	4/26 (15%)
		C2H2 Zn finger	349..368	CDD:275368	5/18 (28%)
		C2H2 Zn finger	376..396	CDD:275368	3/19 (16%)
		C2H2 Zn finger	404..424	CDD:275368	3/20 (15%)
		COG5048	428..840	CDD:227381	67/203 (33%)
		C2H2 Zn finger	432..452	CDD:275368	5/24 (21%)
		C2H2 Zn finger	460..480	CDD:275368	5/19 (26%)
		C2H2 Zn finger	488..508	CDD:275368	6/19 (32%)
		C2H2 Zn finger	516..536	CDD:275368	5/19 (26%)
		C2H2 Zn finger	544..564	CDD:275368	4/19 (21%)
		C2H2 Zn finger	572..592	CDD:275368	8/19 (42%)
		C2H2 Zn finger	600..620	CDD:275368	8/19 (42%)
		C2H2 Zn finger	630..650	CDD:275368
		C2H2 Zn finger	658..678	CDD:275368
		C2H2 Zn finger	686..706	CDD:275368
		C2H2 Zn finger	714..734	CDD:275368
		COG5048	737..1152	CDD:227381
		C2H2 Zn finger	742..762	CDD:275368
		C2H2 Zn finger	770..790	CDD:275368
		C2H2 Zn finger	798..818	CDD:275368
		C2H2 Zn finger	826..846	CDD:275368
		C2H2 Zn finger	854..874	CDD:275368
		C2H2 Zn finger	882..902	CDD:275368
		C2H2 Zn finger	910..930	CDD:275368
		C2H2 Zn finger	938..958	CDD:275368
		C2H2 Zn finger	966..986	CDD:275368
		COG5048	990..1374	CDD:227381
		C2H2 Zn finger	994..1014	CDD:275368
		C2H2 Zn finger	1022..1042	CDD:275368
		C2H2 Zn finger	1050..1070	CDD:275368
		C2H2 Zn finger	1078..1098	CDD:275368
		C2H2 Zn finger	1106..1126	CDD:275368
		C2H2 Zn finger	1134..1154	CDD:275368
		C2H2 Zn finger	1162..1182	CDD:275368
		C2H2 Zn finger	1190..1210	CDD:275368
		COG5048	1214..1641	CDD:227381
		C2H2 Zn finger	1218..1238	CDD:275368
		C2H2 Zn finger	1246..1266	CDD:275368
		C2H2 Zn finger	1274..1294	CDD:275368
		C2H2 Zn finger	1302..1322	CDD:275368
		C2H2 Zn finger	1330..1350	CDD:275368
		C2H2 Zn finger	1358..1378	CDD:275368
		C2H2 Zn finger	1386..1406	CDD:275368
		C2H2 Zn finger	1414..1434	CDD:275368
		C2H2 Zn finger	1442..1462	CDD:275368
		C2H2 Zn finger	1470..1490	CDD:275368
		C2H2 Zn finger	1498..1518	CDD:275368
		C2H2 Zn finger	1550..1570	CDD:275368
		C2H2 Zn finger	1578..1595	CDD:275368
		C2H2 Zn finger	1606..1626	CDD:275368
		C2H2 Zn finger	1634..1654	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910