DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and si:dkey-237m9.1

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_017211095.1	Gene:	si:dkey-237m9.1 / 100329377	ZFINID:	ZDB-GENE-131118-30	Length:	359	Species:	Danio rerio

Alignment Length:	258	Identity:	76/258 - (29%)
Similarity:	119/258 - (46%)	Gaps:	35/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 QDDEDFLRICQESPKSVLEQEEL--ELDLAEISIEVERLDDLNEGPIQSSGFKVEDILNESK--- 139
            ::.|| |:| :|:  ..::||:|  :.||..:..|..:.:::.|        |.:||:.:.|
Zfish     6 EESED-LKI-EET--FTVKQEDLQEQTDLMVLKEETHQWNEMEE--------KHQDIMTDEKRTL 58

  Fly   140 ----INEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEE 200
                .:...|...             :|.....:||..|:.|:.||...:.| .....:|..|::
Zfish    59 TKKTSSRGRPRKS-------------KSKCNFSSKQRRKTFSQKPKLDVHMR-VHKGEKTCTCKQ 109

  Fly   201 CGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYS 265
            ||.......:..:|.:.|.|.|.:.||.|...||.....|.|:|.||||:|:.|:.|.:||....
Zfish   110 CGKSFYTIGNLTVHMRIHTGEKPYTCEQCGKSFCQKENFKTHMRIHTGERPYTCQQCGKSFYHAG 174

  Fly   266 TRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYR 328
            ..:.|.|.||.|||:.|.:|..:|..:..|:.||..|||||.|.|..|.|.|.:..:|..|.|
Zfish   175 NLIMHMRIHTEERPYSCPQCGKSFKQNGNLEVHMRTHTGEKRFTCTQCGKSFVKKQNLDIHMR 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	8/19 (42%)
		zf-H2C2_2	238..262	CDD:290200	11/23 (48%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
si:dkey-237m9.1	XP_017211095.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910