DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and znf341

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001108045.1	Gene:	znf341 / 100136854	ZFINID:	ZDB-GENE-080204-99	Length:	796	Species:	Danio rerio

Alignment Length:	163	Identity:	48/163 - (29%)
Similarity:	72/163 - (44%)	Gaps:	5/163 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 LKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPA 237
            :|..|:...:....::..::...:.|..|.........|..|...|....:|.|:.|:..|.|..
Zfish   514 MKCQSKYSTQEALEQHLLNATHNYPCPHCQKVFPCERYFRRHLSTHGVGGKFKCQICKKFFKTEH 578

  Fly   238 ELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCK-----ECNNAFTTSYILKN 297
            .||.|.:.|:|||||||..|..:|:......:|...|...:.:.|.     .|...|.....||.
Zfish   579 YLKLHTQIHSGEKPFKCSVCEATFNRKDKVKRHMLIHEPFKKYKCPFRTHVGCTKEFNRPDKLKA 643

  Fly   298 HMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSN 330
            |:|.|:|.|.|:|.:|.|.|||..|:..|.||:
Zfish   644 HILSHSGIKPFKCQVCQKSFSRRAHMLEHQRSH 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	20/53 (38%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	4/19 (21%)
		zf-H2C2_2	269..291	CDD:290200	5/26 (19%)
		C2H2 Zn finger	282..302	CDD:275368	7/24 (29%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
znf341	NP_001108045.1	COG5048	295..676	CDD:227381	47/161 (29%)
		C2H2 Zn finger	296..316	CDD:275368
		zf-H2C2_2	308..333	CDD:290200
		C2H2 Zn finger	324..344	CDD:275368
		C2H2 Zn finger	418..438	CDD:275368
		C2H2 Zn finger	446..468	CDD:275368
		C2H2 Zn finger	476..496	CDD:275368
		C2H2 Zn finger	513..535	CDD:275370	2/20 (10%)
		C2H2 Zn finger	539..559	CDD:275368	4/19 (21%)
		C2H2 Zn finger	567..587	CDD:275368	7/19 (37%)
		zf-H2C2_2	579..604	CDD:290200	13/24 (54%)
		C2H2 Zn finger	595..615	CDD:275368	4/19 (21%)
		C2H2 Zn finger	623..648	CDD:275368	7/24 (29%)
		zf-H2C2_2	641..665	CDD:290200	12/23 (52%)
		C2H2 Zn finger	656..676	CDD:275368	9/19 (47%)
		C2H2 Zn finger	684..701	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579936
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930