DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and ZNF730

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_016881603.1	Gene:	ZNF730 / 100129543	HGNCID:	32470	Length:	514	Species:	Homo sapiens

Alignment Length:	322	Identity:	84/322 - (26%)
Similarity:	121/322 - (37%)	Gaps:	82/322 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCL 70
            |..|||..|        :..|.||  |.::.||       ..|.: |..|.....|:.:..|
Human   269 CEKCGKFFN--------QSTNLTT--HKRIHTG-------EKPYK-CEECGKAFNQSSNLTE--- 312

  Fly    71 EVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDIL 135
               .:.:|:::..   ..|::..|:                                 ||....|
Human   313 ---HKKIHTKEQP---YKCEKCGKA---------------------------------FKWSSTL 338

  Fly   136 NESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRN-PRDSNRTFFCE 199
            .:.|          .|...|..|           |.|....:.|.....||.. .....:.:..:
Human   339 TKHK----------RIHNGEKPY-----------KCEECGKAFNRSSTLNRHKITHTGGKPYKYK 382

  Fly   200 ECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDY 264
            |||.......:..:|...|...|.:.||.|...|...:.|..|.|.||||||:||..|.|:|:..
Human   383 ECGKAFNQSSTLTIHKIIHTVEKFYKCEECGKAFSRISHLTTHKRIHTGEKPYKCEECGRAFNQS 447

  Fly   265 STRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTH 326
            ||...|:|.||.|:|:.|:||..||..|..|..|.::|:|||.::|..|.|.|.|::|||.|
Human   448 STLTTHKRIHTGEKPYECEECGKAFNRSSTLTTHKIIHSGEKIYKCKECGKAFRRFSHLTRH 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	16/70 (23%)
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	24/53 (45%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	10/23 (43%)
		C2H2 Zn finger	310..328	CDD:275368	9/17 (53%)
ZNF730	XP_016881603.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000