DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and AZF1

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_014756.3	Gene:	AZF1 / 854280	SGDID:	S000005639	Length:	914	Species:	Saccharomyces cerevisiae

Alignment Length:	353	Identity:	71/353 - (20%)
Similarity:	129/353 - (36%)	Gaps:	99/353 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 AISFRDRCLRSQKIFEESLVR-----NEEDTFRSSVRR-------------------------SA 96
            :::..|....|:|..:|...|     |:||.:.|::.|                         :.
Yeast   403 SLASTDTTSNSRKDLKEIEQRLRKHLNDEDNYSSAISRPLDKNDVIEGSEGLNKHIDESGMQPNI 467

  Fly    97 RSQRQRHEDTA------PKTPASPLEVMIKLESLS---------NGDE---------EDDGIDHL 137
            ..:|::.:.|.      |:|...    |.|..|.|         :|.|         .||..:.:
Yeast   468 IKKRKKDDSTVYVKNEMPRTDPP----MSKDNSTSAEGAAMANFSGKEPPIPDISSVSDDATNLI 528

  Fly   138 DSCNEADMELAIKAMSS------STEDDG-----TTSPVRLKRTRRRGLKKGGKGENRTKVTLPV 191
            .:.....:.|.|:|...      :|..||     .|..:...::...|..:..||...|: .:..
Yeast   529 GATKVDQLMLIIQARKKGFTEKVNTTQDGDLLFNQTMDILPPKSELVGGVEKPKGTQNTR-AVKK 592

  Fly   192 FFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQVMHTGDRKFQCRYCDRT 256
            ..|..|....:..:..:.|:|.|.|.:||.|:.|..||...|.|:.|:.:|||::.:.|..||:.
Yeast   593 HECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKK 657

  Fly   257 YVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHLKT 321
            :........|..||...:||:|                          :.|.|:::|.:..::|.
Yeast   658 FSRKGNLAAHLVTHQKLKPFVC--------------------------KLENCNKTFTQLGNMKA 696

  Fly   322 HFRSNTHKHNLEKSMADAGGVQLSPSQS 349
            | ::..||..|....|..  .:::||::
Yeast   697 H-QNRFHKETLNALTAKL--AEMNPSEN 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	3/15 (20%)
		C2H2 Zn finger	194..214	CDD:275368	4/19 (21%)
		COG5048	<197..322	CDD:227381	30/124 (24%)
		zf-H2C2_2	206..231	CDD:290200	10/24 (42%)
		C2H2 Zn finger	222..242	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	4/19 (21%)
		zf-H2C2_2	265..287	CDD:290200	6/21 (29%)
		C2H2 Zn finger	278..298	CDD:275368	1/19 (5%)
		zf-H2C2_2	291..315	CDD:290200	3/23 (13%)
		C2H2 Zn finger	306..328	CDD:275368	5/21 (24%)
AZF1	NP_014756.3	COG5048	342..768	CDD:227381	71/353 (20%)
		C2H2 Zn finger	595..615	CDD:275368	4/19 (21%)
		C2H2 Zn finger	623..643	CDD:275368	7/19 (37%)
		C2H2 Zn finger	651..671	CDD:275368	4/19 (21%)
		C2H2 Zn finger	679..702	CDD:275368	6/49 (12%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000