DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and si:ch211-79k12.2

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001313520.1	Gene:	si:ch211-79k12.2 / 568844	ZFINID:	ZDB-GENE-131121-535	Length:	555	Species:	Danio rerio

Alignment Length:	300	Identity:	88/300 - (29%)
Similarity:	124/300 - (41%)	Gaps:	80/300 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 CLRSQKIFEESLVRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPLEVMIKLESLSNGDEEDDG 133
            ||..|:.|...                  :|..|||                     .|..:.||
Zfish   250 CLSCQRTFPTC------------------AQLLRHE---------------------QGHAQQDG 275

  Fly   134 IDHLDSCNEADMELAIKAMSSSTEDDGTTSPVRLKRTRR--RGLKKGGKGENRTKVTLPVFFCDQ 196
            :..| ||...:...              ..|.:|.:.:|  ...|.||            |.|.:
Zfish   276 LQQL-SCMHCNASF--------------PRPSQLLQHQRTQHATKAGG------------FLCAE 313

  Fly   197 CGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQVMHTGDRKFQCRYCDRTYVNYS 261
            ||......|:...||..|:|.||:.|..|...|..||.||.|:.:|||:|.:.|.||.|.:.:.:
Zfish   314 CGRAFNSHSNLRIHLNVHTGARPYICTNCGKSFSQSGALKIHRRIHTGERPYTCSYCGRGFPHLA 378

  Fly   262 GRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHLKTHFRSN 326
            |...|:|.||.::|:||.||||.||.|..||.|..||||||.|.|.||.:||:..:.::.|.|:
Zfish   379 GVRAHQRIHTGEKPYICGQCGKCFTQSGALKIHTRIHTGERPFVCGLCGKSFSNRSGIRFHHRT- 442

  Fly   327 THKHNLE------KSMADAGGVQLSPSQ-----SADQVKF 355
            .|...:|      .|:|.:...|:|..|     :.:|:.|
Zfish   443 VHGIVMEPNSVGRPSLAASASSQVSDIQRVQVSAVNQIHF 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	4/8 (50%)
		C2H2 Zn finger	194..214	CDD:275368	6/19 (32%)
		COG5048	<197..322	CDD:227381	55/124 (44%)
		zf-H2C2_2	206..231	CDD:290200	9/24 (38%)
		C2H2 Zn finger	222..242	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		zf-H2C2_2	265..287	CDD:290200	12/21 (57%)
		C2H2 Zn finger	278..298	CDD:275368	11/19 (58%)
		zf-H2C2_2	291..315	CDD:290200	15/23 (65%)
		C2H2 Zn finger	306..328	CDD:275368	7/21 (33%)
si:ch211-79k12.2	NP_001313520.1	C2H2 Zn finger	281..302	CDD:275368	4/34 (12%)
		C2H2 Zn finger	311..331	CDD:275368	6/19 (32%)
		zf-H2C2_2	323..348	CDD:290200	9/24 (38%)
		C2H2 Zn finger	339..359	CDD:275368	8/19 (42%)
		zf-H2C2_2	351..374	CDD:290200	11/22 (50%)
		C2H2 Zn finger	367..387	CDD:275368	7/19 (37%)
		zf-H2C2_2	380..404	CDD:290200	12/23 (52%)
		C2H2 Zn finger	395..415	CDD:275368	11/19 (58%)
		zf-H2C2_2	407..432	CDD:290200	15/24 (63%)
		C2H2 Zn finger	423..442	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910