DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and CG31365

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	82/330 - (24%)
Similarity:	133/330 - (40%)	Gaps:	43/330 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 NSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFR--DRCLRSQKIFE 77
            ||.|.:..|..:.....|.|.:|...:: |.|...:..|..: :::..:.|.  :...:.|::|
  Fly   335 NSASSEDQNQDSTPEFDQDNGITSYNIK-EDGEIQFSGEKPE-EIEDVVVFNLGEEISQEQQVF- 396

  Fly    78 ESLVRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPLEVMIKLESLSNGDEEDDGIDHLDS--C 140
                     :|..:|....:.|..|.|.|..|...|. |::.|.||.....:.....|.:.|  |
  Fly   397 ---------SFHENVIIVEKEQNDRDEQTPLKRKRSS-ELVFKQESSCPQPKTGRITDTVKSFQC 451

  Fly   141 NEADMELAIKAMSSSTEDDGTTSPVRLKRTRRRGLKKGGKGENRTKVTLPVFFCDQCGNNITGKS 205
            :...:....:.:.:           |...|..:|||.|..|      ||.   |..|...::..|
  Fly   452 HLCPVAFPTQKLLT-----------RHHNTHIKGLKSGKGG------TLK---CPSCALQLSCAS 496

  Fly   206 SFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQVMHTGDRKFQCRYCDRTYVNYSGRLRH-ERT 269
            |..||:..|:|::||:|..|...|.....||.|...|||.::.||..|...:...|...:| .|.
  Fly   497 SLKRHMIIHTGLKPFKCSECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGRV 561

  Fly   270 HT-NDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHLKTHFRSNTHKHNLE 333
            |. |.|...|..|.:||.:...|..|::.|.|. :|.|:.|.|.|...:.::.|.   |..|.::
  Fly   562 HMGNSRTHKCHLCHRSFNHVSGLSRHLVTHAGV-MFSCKQCGRQFNDRSAVQRHV---TTMHKVK 622

  Fly   334 KSMAD 338
            ..:.|
  Fly   623 NKLTD 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	13/64 (20%)
		C2H2 Zn finger	194..214	CDD:275368	6/19 (32%)
		COG5048	<197..322	CDD:227381	40/126 (32%)
		zf-H2C2_2	206..231	CDD:290200	10/24 (42%)
		C2H2 Zn finger	222..242	CDD:275368	6/19 (32%)
		C2H2 Zn finger	250..270	CDD:275368	5/20 (25%)
		zf-H2C2_2	265..287	CDD:290200	9/23 (39%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-H2C2_2	291..315	CDD:290200	9/23 (39%)
		C2H2 Zn finger	306..328	CDD:275368	5/21 (24%)
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	24/95 (25%)
		C2H2 Zn finger	485..505	CDD:275368	6/19 (32%)
		zf-H2C2_2	497..522	CDD:290200	10/24 (42%)
		C2H2 Zn finger	513..533	CDD:275368	6/19 (32%)
		zf-H2C2_2	526..550	CDD:290200	9/23 (39%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	571..591	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..617	CDD:275368	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960