DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and CG6813

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	337	Identity:	100/337 - (29%)
Similarity:	150/337 - (44%)	Gaps:	64/337 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFRDRCL 70
            ||:|:.|   ...:.||..|...:::||:.:|||.|.|:..:...||.||..:|::||.||.||:
  Fly     6 CRICSRS---DAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFRQRCI 67

  Fly    71 RSQKIFEESLVRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPLEVMIKLESLSNGDEEDDGID 135
            .::|   ::|.|.|.|:      :...:....:||.                        ||
  Fly    68 IAEK---QNLERIECDS------KDCSTDPIIYEDI------------------------DD--- 96

  Fly   136 HLDSCNEADMELAIKAMSSSTED------DGTTSPVRLKRTRRRGLKKGGKGENRTKVTLPVFFC 194
                 |:.:.||....:....:|      :..::|..|...:..|   ||.|.         :.|
  Fly    97 -----NQIESELDESILCPEVKDLPMPSAEKVSAPTSLNHQKSIG---GGTGP---------YVC 144

  Fly   195 DQCGNNITGKSSFDRHLRKHSGIRPFQCEL--CPARFLSSGELKGHQVMHTGDRKFQCRYCDRTY 257
            ..||..|..||:|..|..:|:||:.|.|..  |...|.:..||..|..:|||::.:.|.||.|.:
  Fly   145 PDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRF 209

  Fly   258 VNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHLKTH 322
            .:...|..|.|.|.|:|.:.|..|.|||.:|..|:.|.:||...|...|.:|.:.|.|.:||.||
  Fly   210 SSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTH 274

  Fly   323 FRSNTHKHNLEK 334
            ..||.||...||
  Fly   275 LSSNIHKRKEEK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	26/71 (37%)
		C2H2 Zn finger	194..214	CDD:275368	8/19 (42%)
		COG5048	<197..322	CDD:227381	47/126 (37%)
		zf-H2C2_2	206..231	CDD:290200	9/26 (35%)
		C2H2 Zn finger	222..242	CDD:275368	6/21 (29%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		zf-H2C2_2	265..287	CDD:290200	10/21 (48%)
		C2H2 Zn finger	278..298	CDD:275368	8/19 (42%)
		zf-H2C2_2	291..315	CDD:290200	8/23 (35%)
		C2H2 Zn finger	306..328	CDD:275368	10/21 (48%)
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	27/75 (36%)
		C2H2 Zn finger	144..164	CDD:275368	8/19 (42%)
		C2H2 Zn finger	172..194	CDD:275368	6/21 (29%)
		zf-H2C2_2	186..211	CDD:290200	10/24 (42%)
		UFD2	<256..>294	CDD:227443	14/31 (45%)
		C2H2 Zn finger	258..280	CDD:275368	10/21 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060