DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and CG31388

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	437	Identity:	106/437 - (24%)
Similarity:	167/437 - (38%)	Gaps:	122/437 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LQNVCRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFR 66
            ::.:||.|:...|.:.:..||:..:..||:||..||.:.|:.:..||.:||:.||.||:.||.||
  Fly     1 MRYICRTCSRMADPAVAKNLFDPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFR 65

  Fly    67 DRCLRSQKIFEESL--VRNEEDTFRSSVRR--------------------------SARSQRQRH 103
            ..|:.:|::.|..|  |..||:.|.|...:                          ....|.:..
  Fly    66 RVCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDPEPQDKNT 130

  Fly   104 EDTAPKTPASPLEVMIKLES---------------LSN----------GDEEDDGIDHLD----- 138
            ::.|.....:..|.|...:|               |||          .:.|.:.||:.|
  Fly   131 DELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEAIDNRDTSSSH 195

  Fly   139 SCNEADMELA-----------IKAMSSSTE------DDGTTSPVRLKRTRRRGLKKGGKGENRTK 186
            :|::..:|..           :..:...|:      |:|..|...|.|             :...
  Fly   196 TCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTR-------------HCNM 247

  Fly   187 VTLPV-------------------------------FFCDQCGNNITGKSSFDRHLRKHSGIRPF 220
            :.||:                               ..|..||.::|...:...||.:|:|.|..
  Fly   248 INLPLTHSCTKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRH 312

  Fly   221 QCELCPARFLSSGELKGHQVMHTGDRKFQCRY-CDRTYVNYSGRLRHERTH--TNDRPFICAQCG 282
            :|:.|.|.|.::.||..||..||.:|.:.||| |.:|:...|.|..|||.|  .:.|.:.|..|.
  Fly   313 KCDQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCP 377

  Fly   283 KSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHLKTHFRSNTHK 329
            ||:......:.|...|...|...||:|..||....|.::|.:||.||
  Fly   378 KSYVTPSECRTHQKYHNLTRDHGCEICRISFKTAKHYRSHLKSNAHK 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	27/72 (38%)
		C2H2 Zn finger	194..214	CDD:275368	6/19 (32%)
		COG5048	<197..322	CDD:227381	44/127 (35%)
		zf-H2C2_2	206..231	CDD:290200	9/24 (38%)
		C2H2 Zn finger	222..242	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	10/20 (50%)
		zf-H2C2_2	265..287	CDD:290200	9/23 (39%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		zf-H2C2_2	291..315	CDD:290200	8/23 (35%)
		C2H2 Zn finger	306..328	CDD:275368	9/21 (43%)
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	27/71 (38%)
		C2H2 Zn finger	228..254	CDD:275368	7/38 (18%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	8/19 (42%)
		C2H2 Zn finger	342..363	CDD:275368	10/20 (50%)
		C2H2 Zn finger	373..393	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..419	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960