DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and ouib

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	133/348 - (38%)
Similarity:	192/348 - (55%)	Gaps:	53/348 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLQNVCRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISF 65
            ||..|||||.......|||.||:....|.|:.:::::|:.|.....:|.:||..||.:|:||::|
  Fly     1 MLNIVCRVCGRQKICEKSLNLFDLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALAF 65

  Fly    66 RDRCLRSQK---IFEESLVRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPLE----VMIKLES 123
            |..|:::|.   ..|:.....:|||..:|   ...|::....|...|.....:|    |:|:.|.
  Fly    66 RKLCIKTQTKWLTIEDDSSSGDEDTNDNS---ELESEKCAFSDFGKKKEGELVEETFQVLIEEEP 127

  Fly   124 LS---NGDEE----DDGIDHLDSCNEADMELAIKAMSSSTEDDGTTSPVRLKRTRRRGLKKGGKG 181
            :.   |.|.:    :||||  :.|..:...:.:.
  Fly   128 MDKTLNRDAKAQLREDGID--EKCVPSQKIIKVS------------------------------- 159

  Fly   182 ENRTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQVMHTGDR 246
               ||:...::.|:.||.:.|.|.:|.||:|||.|.|||.|:.|.|||||:|||:.|..:|||::
  Fly   160 ---TKLDDQIYICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAGELRAHHRVHTGEQ 221

  Fly   247 KFQCRYCDRTYVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHR 311
            .|.||:|::.||:|.|||.||||||||||::|.:|||.||.:|:|||||:||||||.|||::|.|
  Fly   222 PFACRFCEKRYVSYMGRLIHERTHTNDRPYVCEECGKKFTTAYVLKNHMVIHTGERNFRCDICDR 286

  Fly   312 SFARPTHLKTHFRSNTHKHNLEK 334
            ||.|..||.||.||..|..|::|
  Fly   287 SFQRKAHLVTHTRSMMHLQNVKK 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	26/75 (35%)
		C2H2 Zn finger	194..214	CDD:275368	9/19 (47%)
		COG5048	<197..322	CDD:227381	76/124 (61%)
		zf-H2C2_2	206..231	CDD:290200	15/24 (63%)
		C2H2 Zn finger	222..242	CDD:275368	11/19 (58%)
		C2H2 Zn finger	250..270	CDD:275368	12/19 (63%)
		zf-H2C2_2	265..287	CDD:290200	15/21 (71%)
		C2H2 Zn finger	278..298	CDD:275368	12/19 (63%)
		zf-H2C2_2	291..315	CDD:290200	18/23 (78%)
		C2H2 Zn finger	306..328	CDD:275368	12/21 (57%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	26/72 (36%)
		COG5048	<158..300	CDD:227381	81/175 (46%)
		C2H2 Zn finger	169..189	CDD:275368	9/19 (47%)
		C2H2 Zn finger	197..217	CDD:275368	11/19 (58%)
		zf-H2C2_2	209..234	CDD:290200	11/24 (46%)
		C2H2 Zn finger	225..245	CDD:275368	12/19 (63%)
		zf-H2C2_2	241..262	CDD:290200	15/20 (75%)
		C2H2 Zn finger	253..273	CDD:275368	12/19 (63%)
		zf-H2C2_2	266..288	CDD:290200	16/21 (76%)
		C2H2 Zn finger	281..299	CDD:275368	10/17 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447749
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890