DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and CG14667

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	101/359 - (28%)
Similarity:	158/359 - (44%)	Gaps:	55/359 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LQNVCRVCASS-TDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISF 65
            |.:|||:||:. ..:.:...:|.....|.|.|:.|:|||.|....|||:.:||.|.::|..|..|
  Fly     3 LADVCRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDLATKF 67

  Fly    66 RDRCLRSQKIFEESLVRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPL-EVMIKLESLSNGDE 129
            |:||:.|||...: :::...|  :|:|.....|:              || |.:|..:.|....:
  Fly    68 RERCIFSQKYLLD-IIKKTSD--QSTVHVELSSE--------------PLDEQLIDADQLETHYD 115

  Fly   130 EDDGI-------DH-------LDSCNEADMELAIKAMSSSTEDDGTTSPVRLKRTRRRGLKKGGK 180
            :|..:       :|       ||....|.:..|.:|.:.:.:.:........:..:||.
  Fly   116 DDQYVCYQGTKEEHQDLEEIELDDDPSAAVIAAAEAAAEAAQQEDLQEQEMERAAKRRS------ 174

  Fly   181 GENRTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRP----FQCELCPARFLSSGELKGHQV- 240
                     ..|.||:||........:..||..|...|.    |.|..||..|.....||.|:.
  Fly   175 ---------NFFICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQ 230

  Fly   241 MHTGDRKFQCRYCDRTYVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGE-RLF 304
            :|..:|:|||..|...:.:...:|||::.|.|:||:.|.:||..|::...|:||...|:.: |.|
  Fly   231 VHLINRRFQCTICHEAFASLGAKLRHDKAHKNERPYPCLECGMIFSSVSELQNHFSTHSKQIRKF 295

  Fly   305 RCELCHRSFARPTHLKTHFRSNTHKHNLEKSMAD 338
            |||.|:..|.....|..|.::..|| .|.|.|.|
  Fly   296 RCEPCNMDFITRRGLVAHTKTAPHK-RLAKYMQD 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	29/73 (40%)
		C2H2 Zn finger	194..214	CDD:275368	6/19 (32%)
		COG5048	<197..322	CDD:227381	43/130 (33%)
		zf-H2C2_2	206..231	CDD:290200	9/28 (32%)
		C2H2 Zn finger	222..242	CDD:275368	7/20 (35%)
		C2H2 Zn finger	250..270	CDD:275368	5/19 (26%)
		zf-H2C2_2	265..287	CDD:290200	10/21 (48%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		zf-H2C2_2	291..315	CDD:290200	11/24 (46%)
		C2H2 Zn finger	306..328	CDD:275368	6/21 (29%)
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	29/73 (40%)
		C2H2 Zn finger	179..199	CDD:275368	6/19 (32%)
		C2H2 Zn finger	211..232	CDD:275368	7/20 (35%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-C2H2_8	243..313	CDD:292531	24/69 (35%)
		C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960