DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8159 and CG17359

DIOPT Version :9

Sequence 1:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	336	Identity:	91/336 - (27%)
Similarity:	150/336 - (44%)	Gaps:	47/336 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LQNVCRVCASSTDNSKSLKLFN---SGACKVLQQINLLTGVLLQC-------EPGLPDWMCETCQ 56
            :..:||||...:|  ..|.::.   :.:.:|.:|..:|..:|.:|       |.|:|.::|..|.
  Fly     3 ISQMCRVCRDESD--CLLDIYTEPYASSNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECA 65

  Fly    57 TDLKSAISFRDRCLRSQKIFEE-SLVRNEEDTFRSSVRRSARSQRQRHEDT--APKTPASPLEVM 118
            ..:::|...|.:|.:|.:.||: .|:..|.|.....:......:.|.....  |.|||.:...::
  Fly    66 EAVRNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEPLL 130

  Fly   119 IKLESLSNGDEEDDGIDH-LDSCNEADMELAI----------KAMSSSTEDDGTTSP-------- 164
            ::|..:.....|...|.. |...||..:..:.          |..:.|..|:.:.||
  Fly   131 VELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDNDSWSPDSELEHED 195

  Fly   165 -VRLKRTRRRGLKKGGKGENRTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPAR 228
             .::....:||..|...|..|         |..|..:.|.|.:.:.|:|.|:|.||::|.|||..
  Fly   196 DDKIWNASKRGKPKRVPGPYR---------CKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRS 251

  Fly   229 FLSSGELKGHQVMHTGDRKFQCRYCDRTYVNYSGRLR-HERTHTNDRPFICAQCGKSFTNSYILK 292
            |...|.|:.|...|||:|.|.|..|.:.: ...|:|: |.||||.::||.|::|.:||.....|:
  Fly   252 FAQKGNLQSHTRCHTGERPFGCPNCPKRF-RQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQ 315

  Fly   293 NHMLIHT-GER 302
            .||..|| |:|
  Fly   316 KHMSAHTRGKR 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	21/82 (26%)
		C2H2 Zn finger	194..214	CDD:275368	6/19 (32%)
		COG5048	<197..322	CDD:227381	44/108 (41%)
		zf-H2C2_2	206..231	CDD:290200	11/24 (46%)
		C2H2 Zn finger	222..242	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	6/20 (30%)
		zf-H2C2_2	265..287	CDD:290200	11/22 (50%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		zf-H2C2_2	291..315	CDD:290200	7/13 (54%)
		C2H2 Zn finger	306..328	CDD:275368
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	22/83 (27%)
		zf-C2H2	215..237	CDD:278523	7/30 (23%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		zf-H2C2_2	229..254	CDD:290200	11/24 (46%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	9/25 (36%)
		C2H2 Zn finger	273..293	CDD:275368	6/20 (30%)
		zf-H2C2_2	286..310	CDD:290200	12/23 (52%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000